L9&10 - Pulmonary System Flashcards

1
Q

how is the respiratory system organized for breathing?

A

organized like a tree, each section branches into smaller sections

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2
Q

what allows bronchioles to alter diameter?

A

they have a considerable amount of smooth muscle and are controlled by the sympathetic nervous system

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3
Q

describe pulmonary ventilation?

A

Q= ΔP/R
air flows from area of higher pressure to area of lower pressure which then causes changes in the volume of the lungs

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4
Q

how does Boyle’s Law apply to inhalation?

A

during inspiration, diaphragm contracts - volume of thorax increases and pressure within it falls allowing air to flow from outside into the lungs

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5
Q

how does Boyle’s Law apply to exhalation?

A

the inhalation process is reversed aided by the elastic recoil tendency of the lungs, therefore expiration is passive

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6
Q

what is lung compliance?

A

for a given change in pressure, there is a large change in volume - compliance reduced the work of breathing

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7
Q

give an example of lung over-compliance and under-compliance

A

over-compliance = emphysema
under-compliance = fibrosis

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8
Q

what is surfactant?

A

liquid produced by certain alveolar cells and lines the inner surface of the alveoli

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9
Q

when does production of surfactant start?

A

in utero

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10
Q

what are the 3 functions of surfactant?

A
  1. reduces surface tension - high surface tension would allow collapse of alveoli
  2. helps to keep airways open and therefore increases lung compliance
  3. presence of surfactant reduces the work of breathing
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11
Q

what is tidal volume?

A

the volume of air moved in and out of the lungs during a normal breath

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12
Q

what is the formula for minute volume?

A

TV x RR

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13
Q

what is expiratory reserve volume?

A

the volume of extra air breathed out after a normal exhalation

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14
Q

what is inspiratory reserve volume?

A

the volume of extra air breathed in after a normal inhalation

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15
Q

what is forced vital capacity?

A

strongest exhale over 1 second - recorded on a peak flow meter

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16
Q

what is functional residual capacity?

A

the volume of air in the lungs after a normal exhalation

17
Q

what is residual volume?

A

volume of air left in the lungs after a maximum exhalation

18
Q

what is vital capacity?

A

maximum amount of air that can be moved in and out of the lungs in a single breath

19
Q

what is partial pressure?

A

each gas in the air exerts an indiviaual partial pressure
PN2 Po2 Pco2 PH2O
total atmospheric pressure of 760mmHg

20
Q

what is nitrogen’s atmospheric pressure compared to alveolar pressure?

A

597mmHg vs 573mmHg

21
Q

what is oxygen’s atmospheric pressure compared to alveolar pressure?

A

159mmHg vs 100mmHg

22
Q

what is carbon dioxide’s atmospheric pressure compared to alveolar pressure?

A

0.3mmHg vs 40mmHg

23
Q

what is water vapour’s atmospheric pressure compared to alveolar pressure?

A

3.7mmHg vs 47mmHg

24
Q

what 4 factors influence the diffusion of respiratory gasses across the respiratory membrane?

A
  1. surface area available
  2. thickness of the respiratory membrane and its permeability
  3. partial pressure gradient of the gases
  4. lipid solubility
25
Q

describe the intake of O2 during gas exchange

A

O2 diffuses down its concentration gradient across the respiratory membrane from the alveoli into the pulmonary capillaries, where most of it is transported around the circulation bound to haemoglobin
a small amount of it is dissolved in plasma

26
Q

describe the uptake of CO2 into the alveoli to be exhaled during gas exchange

A

CO2 diffuses down its concentration gradient across the respiratory membrane from the pulmonary capillaries into the alveoli to be exhaled