Antigen 11-20

Question 1

Immunogenicity

Answer 1

is not a property of haptens.

Question 2

Lymphocytes are activated by antigen in the

Answer 2

lymph nodes.

Question 3

A molecule that can be covalently linked to a non-immunogenic antigen to make it an immunogen is called a(n)

Answer 3

carrier

Question 4

A polyclonal antibody response

Answer 4

is produced by several B cells recognizing different epitopes on the same antigen.

Question 5

Very low doses of antigen may induce

Answer 5

low zone tolerance.

Question 6

A virus vaccine that can activate cytotoxic T cells MUST contain

Answer 6

live virus.

Question 7

Which statement about antigen epitopes is FALSE?

A. an epitope may be shared by two different antigens.
B. a protein molecule usually contains multiple epitopes.
C. B cells bind only processed antigen epitopes.
D. epitopes may be linear or assembled.
E. some epitopes are more immunogenic than others.

Answer 7

C. B cells bind only processed antigen epitopes.

Question 8

CD antigens

Answer 8

function as receptors for cytokine and CAMs.

Question 9

A patient desperately needs a bone marrow transplant, and a perfect match cannot be found. The rejection response in unmatched marrow is primarily due to the presence of mature T cells that recognize the recipient’s cells as foreign. To minimize this rejection response, the marrow can be treated before transfusion into the recipient with complement plus antibody to human

Answer 9

CD3

Question 10

Antibody to membrane receptors sometimes inhibits receptor function and sometimes mimics the action of the normal receptor ligand. (For example, some antibodies to insulin receptor block the action of insulin and some mimic the action of insulin.) An antibody which should NOT either block or stimulate B cell function would be anti-

Answer 10

CD56