Cytokines 8-13

Question 1

The ability of a cytokine to change gene expression in the target cell is influenced by all of the following EXEPT:

A. presence of a high-affinity receptors on the target cell.
B. precense of soluble cytokine receptors.
C. proximity of the producing and target cells.
D. Rate of transport of cytokine-receptor complexes into the cytoplasm.
E. simultaneous production of another cytokine whose receptor uses the same signal transducing subunit.

Answer 1

D. Rate of transport of cytokine-receptor complexes into the cytoplasm.

Question 2

Cytokines are NOT:

Answer 2

Stored in the cell for qick release.

Question 3

The IL-2R subfamily consists of receptors for IL-2, IL-4, IL-7, IL-9, and IL-15.
This group of cytokine receptors:

Answer 3

Each has a unique high a chain . Affinity cytokine-specific.

Question 4

An antagonist for cytokine X may NOT be:

Answer 4

Cytokine B which acts synergistically with cytokine X.

Question 5

A knock-out mouse for a particular cytokine allows immunologists to characterize cytokine function:

Answer 5

On all cell types simultaneously.

Question 6

Activated Tc can regulate immune responses by signaling activated lymphocytes to undergo:

Answer 6

Apoptosis