CABS: ILD Flashcards

1
Q

Zone 1 of lungs -

A

alveolar pressure is greater than capillary thus collapsing it

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2
Q

Zone 2 of lungs -

A

above the LA the alveolar pressure > venous but not arterial

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3
Q

Zone 3 of lungs -

A

base, low alveolar pressure, higher vasculature pressure, alveolar more compliant

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4
Q

ILD leads to pulmonary fibrosis where

A

in the parenchyma

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5
Q

Airspace vs ILD

A

airspace - alveolar disease
ILD - infiltrative disease leading to fibrosis of the lungs

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6
Q

ILD is a ______ disorder

A

progressive

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7
Q

Idiopathic Pulmonary fibrosis causes

A

start of process not clear
likely associated with:
smoking, GERD, pollution

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8
Q

IPF is loss of

A

type 1 epithelial cells (structure)

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9
Q

Type 2 overgrowth leads to

A

not allowing for repair/ regrowth of the damaged epithelium

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10
Q

IPF on CXR, HRCT will see

A

basilar opacities, honeycombing

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11
Q

IPF may require ____ for dx

A

bx

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12
Q

pneumoconiosis is m/c associated with what causative agents

A

silica, asbestos, coal

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13
Q

Presentation of pneumoconiosis

A

cough
dyspnea
diminished lung volumes
progress to hypoxemia

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14
Q

Coal workers pneumoconiosis m/c occurs in pts

A

who work >20 yrs in coal mine
specifically high carbon coal - may contain silia

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15
Q

Black masses m/c in the (what fields)

A

upper posterior lung fields

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16
Q

Presentation of pneumoconiosis

A

melanoptysis**
cough
progressive dyspnea
pulm HTN
RV failure

17
Q

Silicosis associated with what causative agents

A

inhalation of crystalline silica

18
Q

Silicosis has deposition of silica dust where

A

within the terminal bronchioles and alveoli

19
Q

direct toxic reaction to the silica =

A

breaks down type 2 cells

20
Q

Asbestosis is

A

silicate which was used industrially for construction

21
Q

Asbestos is found in

A

old homes ships and mines

22
Q

Asbestosis forms _____ years after exposure

A

15 years

23
Q

Asbestos causes

A

direct lung injury d/t fiber microtrauma

24
Q

Sarcoidosis is a ________ disease

A

granulomatous

25
Q

On exam in sarcoidosis shows

A

non-caseating granulomas
may appear similar to TB or fungal infections

26
Q

Sarcoidosis causes destruction of the

A

capillary perfusion membrane, formation of granulomas, inflammation

27
Q

Hypersensitivity Pneumonitis is when

A

parenchymal inflammation secondary to immune reaction to inhaled noxious stimuli

28
Q

m/c subtype of Hypersensitivity Pneumonitis

A

farmer’s lung

29
Q

Clubbing is a result of

A

chronic hypoxemia
increased fingertip mass with increased curvature

30
Q

Hypoxemia =

A

decreased O2 in arterial blood

31
Q

Hypoxia =

A

decreased O2 to tissues