Hematology Transfusion Medicine

Question 1

Transfusion of one unit of PRBCs raises

the hematocrit level by ….?

and the Hb level by ……?

Answer 1

HCT by 3%

Hb by 1 g/dl ( 10 g/L)

Question 2

Platelet transfusions in neurosurgery or active bleeding

Answer 2

Plt < 100

Question 3

Platelet transfusions in undergoing general surgery

Answer 3

Plt < 50

Question 4

Platelet transfusions in acute promyelocytic leukemia

Answer 4

Plt < 30 - 50

Question 5

Platelet transfusions to prevent spontaneous bleeding in most stable, afebrile patients

Answer 5

Plt < 10

Question 6

Transfusion complications

Answer 6

Hemolytic reaction

Non hemolytic reaction

Question 7

Hemolytic reactions

Answer 7

Acute ( fever , flank pain, hypotension, bleeding, DIC, hemoglobinuria,death)

Delayed ( 7-14 days after transfusion, +DAT )

Question 8

Non hemolytic reactions

Answer 8

1. TACO
   2.TRALI
   3.febrile
   4.allergic reaction

Question 9

TRALI treatment

Answer 9

Supportive
O2
Mechanical ventilation

Question 10

SOB, fever , Hypotension, no signs of volume overload

Answer 10

TRALI

Question 11

TACO treatment

Answer 11

Diuretics
Slower rate of blood administration

Question 12

Respiratory distress, elevated CVP, high BNP , pulmonary Odema

Answer 12

TACO