Antiphospholipid syndrome Flashcards
1
Q
What are the 3 characteristic features of antiphospholipid syndrome?
A
- Thrombocytopenia
- Recurrent miscarriages
- Increased venous and arterial thrombosis
2
Q
It commonly occurs secondary to what condition?
A
SLE
3
Q
Antiphospholipid syndrome causes a paradoxical rise in what?
A
APTT
4
Q
Name an antibody that’s associated with antiphospholipid syndrome
A
- Anticardiolipin antibody
- Anti beta 2 glycoprotein 1 antibody
- Lupus anticoagulant
5
Q
In the management of antiphospholipid syndrome, what is given for primary thromboprophylaxis?
A
Low dose aspirin
6
Q
In the management of antiphospholipid syndrome, what is given for secondary thromboprophylaxis?
A
Warfarin with target INR 2-3
