7 - Cell Cycle, mitosis and meiosis Flashcards

1
Q

Telomeres

A

G rich ends of chromosomes

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2
Q

Cohesins

A

proteins that join sister chromatids

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3
Q

Kinetochores

A

Microtubule binding structure, one per chromatid, on either side of centromere. Microtubules attach to both kinetochores and pull sister chromatids apart

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4
Q

What ware spindle microtubules composed of

A

Tubulin subunits

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5
Q

Centrosome

A

Contains two centrioles at right angles. Where microtubules assemble

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6
Q

Nondisjunction

A

Incorrect segregation of chromosomes

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7
Q

homologous chromosomes

A

Two chromosomes in a pair

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8
Q

chromatin

A

decondensed chromosome

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9
Q

Phases of cell cycle

A

G1, S, G2, M

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10
Q

Phases of M phase

A

Prophase, Prometaphase, Metaphase, Anaphase, Telophase

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11
Q

Prometaphase

A

Nuclear membrane disintegrates. Spindle microtubules attach to kinetochores

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12
Q

Prophase

A

Chromosomes condense. mitotic spindle forms

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13
Q

Metaphase

A

Chromosomes line up on metaphase plate

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14
Q

Anaphase

A

Sister chromatids seperate and move towards pols

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15
Q

Results of mitosis

A

2 cells with same number of chromosomes as parent cells (both 2n)

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16
Q

results of meiosis

A

4 cells with half the number of chromosomes as parent cells (each n)

17
Q

Crossing over

A

Unique to meiosis, exchange of genetic material between members of each homologous pair of chromosomes. Allows genetic variation

18
Q

Chiasma

A

Site of crossing over

19
Q

seperation of tetrads during anaphase 1

A

Cohesin along chromosome arms break down allowing homologs to seperate but cohesin at centromere is protected by shugoshin. Shugosin degraded allowing chromatids to seperate.

20
Q

Metaphase in mitosis

A

Individual chromosomes line up

21
Q

Metaphase in meiosis 1

A

Homologous pairs line up

22
Q

Metaphase in meiosis 2

A

Individual chromosomes line up

23
Q

When does crossing over occur

A

prophase 1

24
Q

Random & independent alignment of
chromosomes

A

Metaphase 1

25
Q

Random & independent distribution of chromosomes

A

Anaphase 1

26
Q

Anaphase in mitosis

A

Chromatids seperate

27
Q

Anaphase in meiosis 1

A

Homologous chromosomes seperate

28
Q

anaphase in meiosis 2

A

Chromatids seperate