Complements Association Flashcards
1
Q
C1q, C1rs, C2, C4 deficiency (classical pathway components)
predisposes to
A
immune complex disease
e.g. SLE,
Henoch-Schonlein Purpura
2
Q
C3 deficiency leads to
A
Recurrent bacterial infection
3
Q
C5-9 deficiency leads to ?
A
encodes the membrane attack complex (MAC)
particularly prone to Neisseria meningitidis infection
4
Q
C5 deficiency leads to
A
recurrent diarrhoea,
wasting and
seborrhoeic dermatitis
5
Q
C1-INH
A
strongly associated with hereditary angioedema
