11.4 Cholesterol Metabolism Flashcards
1
Q
How is Cholesterol obtained?
A
Food or synthesis in liver
2
Q
What is Citrate Shuttle?
A
Carries mitochondrial acetyl-CoA into cytoplasm for synthesis
3
Q
What is Mevalonic Acid?
A
The rate limiting step in cholesterol sythesis.
Made in smooth ER
4
Q
What is HMG-CoA reductase?
A
Key enzyme in cholesterol biosynthesis
5
Q
What is LCAT?
A
catalyzes the formation of cholesteryl esters for transport with
HDL.
6
Q
What is CETP?
A
catalyzes the transition of IDL to LDL by transferring
cholesteryl esters from HDL.
