L9_Dynamics of the Host-Parasite Relationship Flashcards

1
Q

Our relationship with most of our normal flora is best described as?

A

Commensalism

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2
Q

What are the most common skin commensals, which is the most dangerous opportunistic pathogen?

A

Staph epidermidis, Candida Albicans, and Staph Aureus. If not contained properly, staph aureus will cause disease (i.e. broken skin)

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3
Q

What does commensalism on the skin assume?

A

The skin is not broken

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4
Q

What does commensalism in the Respiratory Tract Assume?

A

The host is immunocompetent

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5
Q

What are the most common commensals in the Nose and Throat? Which species can cause problems if over grown?

A

Wide variety of commensals including Strep, Staph, and Nisseria. Problems with overgrowth of S. Pyogenes, N. Meningitidis, and S. Aureus

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6
Q

What commensal in the mouth can cause cavities and heart valve disease if hygiene is poor? Name two other commensals in the mouth

A

S. Mutans….Actinomyces (causes that buldge along the chin) and Kingella Kingae

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7
Q

Describe the colonization of the stomach, small intestine and large intestine.

A

Stomach usually free of bacteria, small intestine has strep, lactobacilli, and yeast, and the large intestine is totally full of a large variety which are mostly anaerobes (coliforms).

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8
Q

Name two examples of true symbiotes

A

Nutrient generating bacteria in gut and Lactobacillus in the vagina

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9
Q

How do commensals contribute to the innate immune system?

A

Colonization resistance

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10
Q

Describe the steps of Koch’s Postulate.

A

Observe disease, culture pathogen, infect new host, observe same disease, culture same pathogen.

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11
Q

What does lactobacillus help do in the vagina?

A

Keep a low pH

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12
Q

What type of overgrowth can happen in vagina if pH rises?

A

Candida (yeast infection)

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13
Q

What is a danger to neonates from mothers commensals if delivered vaginally without antibiotics?

A

Group B strep (sepsis and Meningitis)

Also S. Aureus

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14
Q

Why is it difficult for most species to colonize on the skin?

A

Acid pH, Dry

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15
Q

List the chemical components of the innate immune system

A

Acid pH on skin, stomach, and vagina
lysozyme
Defensisns

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16
Q

List the microbiological component of the innate immune system

A

Colonization Resistance

17
Q

List the Immunochemical components of the innate immune system

A

Fever, Interferon

18
Q

List the Cellular components of the innate immune system

A

Macrophages and complement