Exam Likely Flashcards

1
Q

Side effect of penicillin?

A

Interstitial nephritis

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2
Q

Adverse reaction of cephalosporins?

A

Disulfiram like reactions

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3
Q

Adverse effects of aminoglycosides?

A

Ototoxicity (especially with loop diuretics)

Nephrotoxicity

Neuromuscular blockade (contraindication myasthenia gravis)

Teratogenicity

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4
Q

Aminoglycosides names?

A

GNATS

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5
Q

Mechanism of aminoglycosides?

A

Bind 30S subunit

Uptake requires oxygen so useless against anaerobes

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6
Q

Cephalosporin generations?

A

See photo

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7
Q

Gout medications and mechanism?

A

Colchicine - inhibits microtubule function in inflammatory cells

Allopurinol - xanthine oxidase inhibitor

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8
Q

Kernicterus?

A
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9
Q

Embrotoxic antibiotics?

A

Tetracycline

Macrolide - clarithromycin

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10
Q

Teratogenic antiviral?

A

Ribageline

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11
Q

Cause of grey baby syndrome?

A

Chloramphenicol

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12
Q

Acute treatment of gout?

A

NSAIDs

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13
Q

Drug when gout is seen with renal disease and gastric ulcer?

A

Colchicine

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14
Q

Colchicine side effects?

A

Diarrhoea

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15
Q

Chronic gout drug

A

Probenecid

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16
Q

Probenecid mechanism?

A

Inhibits reabsorption of urate in the PCT

17
Q

Tumour lysis syndrome drug?

A