TYPES OF ADR (TYPE B)

Question 1

Types of Type B ADR

Answer 1

Idiosyncratic
Immunologic

Question 2

Idiosyncratic adverse drug reactions

Answer 2

Sulfonamides - SJS
Vancomycin - Red man syndrome

Question 3

Sulfonamides - SJS

Answer 3

Idiosyncratic

Question 4

Vancomycin - Red man syndrome

Answer 4

Idiosyncratic

Question 5

Types of Immmunologic reaction

Answer 5

Type I IgE-mediated
Type II Cytotoxic
Type III IgG mediated
Type IV T-cell mediated

Question 6

Penicillin and Cephalosporin

cross reactivity

Answer 6

Type I IgE mediated

Question 7

Dextrans (Plasma expander)

Answer 7

Type I IgE mediated

Question 8

X-ray contrast media

Answer 8

Type I IgE mediated

Question 9

Chloramphenicol - aplastic anemia

Answer 9

Type II Cytotoxic

Question 10

Methyldopa - hemolytic anemia

Answer 10

Type II Cytotoxic

Question 11

Aspirin, Ibuprofen - ITP

Answer 11

Type II Cytotoxic

Question 12

Serum sickness

Answer 12

Type III IgG mediated

Question 13

Soluble antigen

Answer 13

Type III IgG mediated

Question 14

Drug-induced SLE (HIPS)

Answer 14

Type III IgG mediated

Question 15

JHR (Jarisch Herxheimer Reaction)/Die-off reaction

Answer 15

Type III IgG mediated

Question 16

Poison ivy - contact dermatitis

Answer 16

Type IV T-cell mediated

Question 17

Tissue/organ rejection

Answer 17

Type IV T-cell mediated

Question 18

Mantoux test

Answer 18

Type IV T-cell mediated