#14 Flashcards
1
Q
iCapacitor
A
Supplies internal positive charges to maintain Vm at Vcom
2
Q
iLeak
A
Current that is results of K naturally exiting and Na naturally entering
3
Q
iLeak Equation
A
= gLeak (Vm - Vleak)
4
Q
Current Measured During Voltage Clamp
A
iM = Total Membrane Current
5
Q
TTX
A
Blocks V(Na) channels
6
Q
TEA
A
Blocks V(K) channels
7
Q
HH Removed…
A
iNa(v) leaving them with purely K
No inward current = No AP
8
Q
What happens if you removed [K+]o?
A
Outward current gets bigger
Higher DF
9
Q
HH Deduced Inward iNa(V)
A
By subtracting outward current iK(V) from current trace after Na+ is removed
10
Q
Na(V) Channel Gates at Vrest
A
Activation Gate = Closed (Opened by Depol)
Inactivation Gate = Open (Closed by Depol)
11
Q
Na+ Ions can only flow when both channels are…
A
Open. Briefly
