blood administration Flashcards

1
Q

blood components

A

RBC, plasma, platelets, cryoprecipitate

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2
Q

cryoprecipitate

A

comes from plasma after freeze-thaw cycle
- mainly fibrinogen
- given to people with low fibrinogen

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3
Q

FFP

A

can be stored for a year
- does not provide platelets
- typical volume is 200-250

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4
Q

Rh

A

identifies whether a persons blood type is negative or positive

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5
Q

Blood group O antigen and antibodies

A
  • no antigens on red cells
  • anti A and anti B antibodies in plasma
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6
Q

blood group A antigen and antibodies

A
  • “A” antigens on red cells
  • anti B antibodies in plasma
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7
Q

blood group B antigen and antibodies

A
  • “B” antigens on red cells
  • anti A antibodies in plasma
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8
Q

blood group AB antigen and antibodies

A
  • A and B antigens on red cells
  • no antibodies in plasma
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9
Q

O negative compatibility to RBC and plasma

A
  • compatible to O negative RBC
  • can have any plasma
  • universal RBC donor
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10
Q

O positive compatibility to RBC and plasma

A
  • compatible to O + and O - RBC
  • can have any plasma
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11
Q

A negative compatibility to RBC and plasma

A

RBC: A- O-
Plasma: A, AB

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12
Q

A positive compatibility to RBC and plasma

A

RBC: A+,A-,O+,O-
plasma: A and AB

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13
Q

B negative compatibility to RBC and plasma

A

RBC: B-, O-
Plasma: B and AB

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14
Q

B positive compatibility to RBC and plasma

A

RBC: B+,B-,O+,O-
Plasma: B and AB

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15
Q

AB negative compatibility to RBC and plasma

A

RBC: AB-,A-,B-,O-
Plasma: only AB

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16
Q

AB positive compatibility to RBC and plasma

A

RBC: universal receiver of RBC
Plasma: only AB

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17
Q

PRBC indications for use

A
  • chronic or symptomatic anemia (fatigue, SOB, reduced O2)
  • Restoration of blood volume
  • dont treat with hemoglobin unless 70
  • typical bag volume is 250ml
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18
Q

PRBC effect on hemoglobin and hematocrit

A

raises hemoglobin 1g/dL
raises hematocrit 3%

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19
Q

indication for administration of plasma

A

procoagulant deficiencies; DIC; trauma

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20
Q

indication for administration of platelets

A

control bleeding in platelet deficiency; thrombocytopenia

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21
Q

gauge sizing

A

22-14 appropriate but 20-18 better for general population

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22
Q

priming solution for blood

A

only use normal saline

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23
Q

filter for blood admin

A

170 micron filter

24
Q

administration time

A

within 4 hours

25
Q

Platelet indications for use

A

control bleeding in deficiency (thrombocytopenia), count less than 50,000, surgery with count less than 100,000, non-bleeding patients with rapidly dropping platelets less than 15,000

26
Q

platelet admin guidelines

A

*admin 1 unit over 5-10 min
- 1 unit will raise platelets from 5 to 10,000
- usually admin 6-8 units at once

27
Q

indications for plasma admin

A

procoagulant deficiencies, DIC, trauma

28
Q

vitals for blood admin

A

within 30 min before administration, after 15 min, then every 1 hour

29
Q

post transfusion VS

A

right when blood is done then monitor PRN

30
Q

obtaining blood

A

can only get one unit at a time

31
Q

reaction time

A

occurs within first 5-15 min

32
Q

body systems to assess before admin

A

lungs, kidneys, lab values

33
Q

informed consent

A

no time frame for amount of time it lasts but need to re-obtain if condition has changed, patient knowledge has changed, or there is a refusal to part of patient treatment

34
Q

initial infusion rate

A

start transfusion at 50ml/h for first 15 min

35
Q

maximum transfusion time

A

4 hours

36
Q

administration after blood is collected from lab

A

must administer 30 min after getting from lab

37
Q

post transfusion

A

flush line, take vitals, bag and tube must go in biohazard

38
Q

equipment change

A

every 8 hours

39
Q

cutaneous transfusion reaction S&S

A

key sign is urticaria, pruritus, erythema, jaundice, pallor, cyanosis

40
Q

inflammatory transfusion reaction S&S

A

fever, chills, rigor

41
Q

cardiovascular transfusion reaction S&S

A

tachy/bradycardia, hypo/hypertension, JVD

42
Q

respiratory transfusion reaction S&S

A

dyspnea, wheezing, pulmonary edema,

43
Q

GI transfusion reaction S&S

A

nausea, vomiting, diarrhea

44
Q

Acute hemolytic transfusion reaction is caused by…

A

wrong blood to wrong patient or DIC

45
Q

S&S of acute hemolytic transfusion reaction

A

dyspnea, fever, chills, lumbar pain, shock

46
Q

treatment goal for acute hemolytic transfusion reaction

A

achieve and maintain adequate BP, give lasix, make sure urine output is 100ml/h

47
Q

febrile transfusion reaction

A

can be caused by antibodies in blood
- people most at risk are those who have had blood transfusions in the past

48
Q

S&S of febrile transfusion reaction

A

fever and chills

49
Q

treatment for febrile transfusion reaction

A

stop blood, administer antipyretic

50
Q

transfusion related acute lung injury timing

A

occurs hours within infusion
- provide O2 support

51
Q

S&S of transfusion related acute lung injury related to blood flow, blood pressure and lungs

A

hypoxia, pulmonary edema, hypotension

52
Q

Transfusion related circulatory overload

A

fluid is drawn to intravascular space if transfused too quickly
- dyspnea
- administer lasix

53
Q

Cause of citrate toxicity

A

citrate in transfused blood binds calcium to patients body

54
Q

citrate toxicity can cause…

A

hypomagnesia and hypocalcemia

55
Q

transfusion associated graft vs host disease

A

fatal; lymphocytes attack recipient tissue

56
Q

Delayed hemolytic transfusion reaction

A

may present as asymptomatic and can occur up to 4 weeks after infusion
- may have slight fever