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FINALS: Dermatology > Dermatitis Herpetiformis > Flashcards

Dermatitis Herpetiformis Flashcards

1
Q

What is dermatitis herpetiformis?

A

A chronic, autoimmune, blistering skin disease with very itchy papules and vesicles

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2
Q

What is the pathophysiology of dermatitis herpetiformis?

A
  • Strong genetic predisposition
  • HLA-DQ2, HLA-DQ8
  • Main environmental trigger is ingestion of gluten (anti-tTG antibodies form)
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3
Q

How does DH present?

A
  • Symmetrical, erythematous, itchy papules usually on the elbow, knees and buttocks
  • Can present on scalp, face and neck
  • Episodes of exacerbation and remission
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4
Q

How is DH investigated?

A
  • Skin biopsy which shows IgA deposits
  • Serology can detect the anti-tTG antibodies
  • Screening for coeliac disease is recommended
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5
Q

How is DH managed?

A

Lifelong gluten free diet
Dapsone can be given for symptomatic relief

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FINALS: Dermatology (26 decks)

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