Properties Of Sensory and Motor Neuronz Flashcards

1
Q

What are passive electrical properties of neurons

A

Wires conduct current by electron Flow, neurons conduct current by ion flow, in both cases, current flow is impeded by resistance

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2
Q

Neuron can be modelled as a wire

A

.each segment in model has a resistance
.this causes an applied voltage to decay as it travels along neuron
.ultimately the voltage will decay to zero

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3
Q

How do we define the decay of the voltage

A

By 2 peramiters

1.space constant (how far the voltage travels)
2.time constant (how fast)

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4
Q

Describe passive conduction velocity

A

Anything that increases the space constant or reduces the time constant will therefore increase conduction velocity

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5
Q

What is the voltage across a cell membrane determined by

A

A balance between electrical charge and osmotic force i.e balance between electrical charge and osmotic force

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6
Q

Describe chemical and electrical gradients

A
  1. Net extrecellular positive charge under resting condition
    2.hyper polarisation increases this potential (action potential less likely)
    3.de polarisation reduces potential (making action potential more likely)
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7
Q

What is the sodium pump crucial for

A

Establishing the membrane potential necessary for the action potential.

Otherwise sodium and potassium would leak across the membrane, causing the potential to drop to zero

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8
Q

Describe action potential: voltage-gated ion channels

A

1.Ap is mediated by voltage gated ion channels embedded in cell membrane
2.open when a threshold is reached
3.sodium and potassium channels are the primary mediators of action potential

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9
Q

Sodium channel has 3 states:

A

1.open
2.closed
3.deactivated

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10
Q

Potassium channel has 2 states:

A

1.open
2.closed

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11
Q

What is the action potential positive feedback cycle

A

1.cell membrane becomes depolarised

2.once depolarisation reaches a thresh hold sodium channels open

3.causes more sodium to pass through the osmotic gradient and leads to more depolar

4.this opens all adjacent channels causing a chain reaction

5.potassium channels open more slowly and this resulting outflow repolarises membrane potential

6.sodium channels close and temporarily deactivated

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12
Q

What different dynamics do sodium and potassium channels have

A

Na channels open quickly, K channels open more slowly, and this difference is crucial for action potential

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13
Q

What does the refractory period do

A

Prevents the positive feedback continuing indefinitely, this ensures the action potential travels in one direction

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14
Q

What are the effects of neuron diameter

A

Time constant is barely affected

Space constant becomes larger therefore a faster space constant

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15
Q

What is myelin

A

Essentially an insulator wrapped around the axon and neuron

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16
Q

What are the affects of myelin

A

1.increases the space constant

17
Q

What are the effects of myelin and neuron diameter

A

Large diameter axons are faster for both myelinated and unmyelinated fibres