WBC

Question 1

Two type of phagocytes

Answer 1

Mononuclear and granulocytes

Question 2

Types of phagocytes which arise from the bone marrow and are released as monocytes.

Answer 2

Mononuclear

Question 3

How long will it take monocytes to differentiate into becoming macrophages?

Answer 3

Hours to days

Question 4

3 classifications of granulocytes

Answer 4

Neutro, eosino, and baso

Question 5

5 stages of phagocytosis. (In order)

Answer 5

-Chemotaxis

-Attachment to organism

-Ingestion

-Fusion of cell lysosomes with ingested microorganism and bacterial killing

-Digestion

Question 6

Movement of an organism in response to a chemical stimulus

Answer 6

Chemotaxis

Question 7

Where should ingested pathogens bind order to be digested by paghocytes?

Answer 7

Lysosomes

Question 8

WBC responsible for the defense against metazoan parasites and modulating inflammatory processes.

Answer 8

Eosinophils.

Question 9

T or F
Eosinophils respond chemotactically to histamine.

Answer 9

T

Question 10

T or F
Basophils are true phagocytes.

Answer 10

F

Question 11

Granulocyte which contains large amounts of histamine and other mediators of inflammation.

Answer 11

Basophils

Question 12

What controls the production and circulation of WBCsand RBCs?

Answer 12

Colony stimulating factors and interleukins

Question 13

Functions of lymphocytes in terms of different immunity.

Answer 13

Humoral and cellular immunity

Question 14

Where are t-cells produced?

Answer 14

Bone marrow. Once these lynphocytes are produced, they then migrate to thymus and differentiate into different thymic hormones.

Question 15

Where are t-cells mostly located?

Answer 15

Thymus. (Tho some/few are located in the spleen and lymph node.)

Question 16

Differentiate t-lymphocytes and b-lymphocytes in terms of their immunologic responsibilities and location in the lymph node

Answer 16

T- cytotoxic immunity (parafollicular zones)
B - humoral immunity (follicular zones)

Question 17

Lymphocytes are either efferent and afferent.

Answer 17

T

Question 18

How do B-cells react to an antigen?

Answer 18

Thru cloning (division) into plasma cells that produce antibodies.

Question 19

Immunoglobulin which responds first to respiratory and intestinal secretions.

Answer 19

IgA

Question 20

Immunoglobulin which responds first to newly recognized antigen.

Answer 20

IgM

Question 21

Immunoglobulin which responds first to an antigen in the blood.

Answer 21

IgG

Question 22

Immunoglobulin which responds first to allergy

Answer 22

IgE

Question 23

Type of lymphocyte which eliminates foreign cells even without sensitization.

Answer 23

Natural killer cells

Question 24

How do basophils and mast cells induce systemic anaphylaxis?

Answer 24

When exposed to an allergen, IgE are bound on the surface of basophils and mast cells causing degranulation. This results to the release of vasoactive amines (PAF 30k more potent than histamine)

Question 25

Antibody which is a part of the b-cells that activates basophils and mass cells.

Answer 25

IgD (IgE ata to ah)

Question 26

Type of immunity which produces antigen specific antibodies in response to an antigen.

Answer 26

Humoral immunity

Question 27

Type of immunity primarily driven by T-cells

Answer 27

Cell-mediated immunity

Question 28

What cells are responsible for cell-mediated immunity?

Answer 28

T-cells, macrophages, and cytokines