Diseases of the Blood Flashcards

1
Q

intro

What are the main functions of the blood?

A
  1. transport nutrients
  2. removal of waste
  3. trasnport of host defenses
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2
Q

intro

what are the blood constituents?

A
  • cells
  • plasma proteins (albumin and globulin)
  • lipids
  • nutrients
  • water
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3
Q

intro

anaemia

A

decreased Hb

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4
Q

intro

leukopenia

A

decreased white cell count

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5
Q

intro

thrombocytopenia

A

decreased platelets

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6
Q

intro

pancytopenia

A

all cells decreased

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7
Q

what occurs if there is multiple changes with regards to anaemia, leukopenia, thrombocytopenia, pancytopenia?

A

bone marrow failure

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8
Q

intro

polycythaemia

A

increased Hb

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9
Q

intro

leukocytosis

A

increased WCC

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10
Q

intro

throbocythaemia

A

increased platelets

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11
Q

intro

leukaemia

A

neoplastic proliferation of white cells, usally disseminated

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12
Q

Intro

Lymhoma

A

neoplastic proliferation of white cells, usually a solid tumour

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13
Q

intro

which lineage are RBC (erythrocytes) derived from?

A

myeloid stem cell

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14
Q

intro

which lineage are platelets (megakaryocytes) dervied from?

A

myeloid stem cell

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15
Q

intro

where are basophil, neutrophil, eosinphil, and monocytes dervied from?

A

myeloid stem cells

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16
Q

intro

where are B cells and T cells dervied from?

A

lymphoid stem cells

17
Q

intro

give one example of an acute lymphoid malignancy

A

acute lymphoblastic leukaemia

18
Q

intro

give one example of an acute myeloid malignancy

A

acute myeloid leukaemia

19
Q

intro

give 4 examples of a chronic lymphoid malignancy

A
  • chronic lymphocytic lekaemia
  • hodgkin lymphoma
  • non-hodgkin lymphoma
  • multiple myeloma
20
Q

intro

give 2 examples of a chronic myeloid malignancy

A
  • chronic myeloid leukaemia
  • myeloproliferative disorders
21
Q

intro

what is porphyria?
what are the two main types?

A

abnormality of haem metabolism
1. hepatic
2. erythropoietic

22
Q

intro

A