Warfarin Drug and Diet Interactions

Question 1

What are some medications that can increase INR?

Answer 1

-Metronidazole
-Amiodarone
-Fluconazole
-Ciprofloxacin
-Bactrim
-Acute alcohol consumption
-Chronic alcohol consumption with liver damage

Question 2

What are some medications that can decrease INR?

Answer 2

-Rifampin
-Chronic alcohol use without liver damage

Question 3

What are some medications that can increase bleeding risk, but not affect INR?

Answer 3

Aspirin and other NSAIDs

Question 4

Generally what foods are high in vitamin K?

Answer 4

Green leafy vegetables

Question 5

How should you counsel a patient on dietary consumption of foods high in vitamin K?

Answer 5

Do not tell them to stop consumption of foods with high vitamin K and instead tell the patient to stay consistent with their consumption