Additional Drugs with Narrow therapeutic index 2

Question 1

A medication used to treat life threatening ventricular arrhythmias

Answer 1

Procainamide

Question 2

An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.

Answer 2

Fosphenytoin

Question 3

An aminoglycoside used to treat a wide variety of aerobic infections in the body.

Answer 3

Gentamycin

Question 4

A medication used to treat manic episodes of bipolar disorder.

Answer 4

Lithium carbonate

Question 5

A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.

Answer 5

Tacrolimus

Question 6

An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.

Answer 6

Sirolimus

Question 7

A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.

Answer 7

Temsirolimus

Question 8

A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.

Answer 8

Thiopental

Question 9

An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette’s Disorder.

Answer 9

Pimozide

Question 10

A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.

Answer 10

Quinidine

Question 11

An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.

Answer 11

Heparin

Question 12

A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.

Answer 12

Vancomycin

Question 13

A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.

Answer 13

Aminophylline

Question 14

An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.

Answer 14

Amikacin

Question 15

An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.

Answer 15

Amphotericin B

Question 16

An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.

Answer 16

Valproic acid

Question 17

A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.

Answer 17

Amiodarone

Question 17

A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.

Answer 17

Dofetilide

Question 18

A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.

Answer 18

Sotalol

Question 19

A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.

Answer 19

Argatroban

Question 20

A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.

Answer 20

Everolimus

Question 21

An immunosuppressant used to prevent organ transplant rejections.

Answer 21

Mycophenolic acid

Question 22

is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline

Answer 22

Butriptyline

Question 23

A tricyclic antidepressant indicated in the treatment of depressive disorders.

Answer 23

Amitriptylinoxide

Question 24

For the treatment of depression.

Answer 24

Amineptine

Question 25

A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential.

Answer 25

Dosulepin

Question 26

An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder.

Answer 26

Tianeptine

Question 27

An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.

Answer 27

Neomycin

Question 28

An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.

Answer 28

Streptomycin

Question 29

An aminoglycoside used to treat a wide variety of infections in the body.

Answer 29

Netilmicin