phosphoglucomutase (PGlucM) Flashcards
1
Q
What type of mechanism?
A
double SN2, adding a Pi to position 1….
Also has a substrate flip similar to aconitase., 180 degree reorientation.
Substrate now flipped around and can remove Pi from C6.
highly reversible, interconverion between G6P and G1P
2
Q
PGlucM structure
A
monomeric,
active site is located at the bottom of a vry deep crevice…
3
Q
key serine
A
the phosphate located on this serine is mechanistic, because it is the one being transferred in the mechanism.
4
Q
A
