Exchange Surfaces P2 Flashcards
What are adaptions of erythrocytes (RBC’s)
- Biconcave shape maximises SA for gas exchange
- Small and flexible to pass through narrow capillaries
- No nucleus, more room to carry respiratory gases
- Packed with haemoglobin
What is haemoglobin?
- Globular protein
- 1 polypeptide chain
- 1 haem group
- Each haem group has an affinity for oxygen
What is haemoglobin called when it becomes oxygenated?
- Oxyhaemoglobin
What is partial pressure?
- The amount of oxygen in any tissue
Explain foetal haemoglobin
- Higher affinity for oxygen than adult haemoglobin
- Must be able to associate oxygen from an environment that makes adult haemoglobin release oxygen
- Foetus gains oxygen from mother at placenta which contains oxygenated blood
How is CO2 removed ?
- 5% dissolves directly into plasma
- 10% combines with haemoglobin
- 85% transported as hydrocarbinate ions
How is carbonic acid formed ?
- As Co2 diffuses into blood, some enters RBC’s
- Combines with water to form weak acid = carbonic acid
- Reaction is catalysed by enzyme
What is dissociation within carbonic acid?
- Carbonic acid dissociates and releases hydrogen ions and hydrogen carbonate ions
What is the chloride shift?
- Hydrogen carbonate ions diffuse out of RBC’s into plasma by diffusion
- Change inside cell is maintained by movement of chloride ions from plasma into RBC
Why is haemoglobinic acid produced?
- To removed hydrogen ions and maintain pH of RBC
What is the Bohr effect?
- Hydrogen ions released from dissociation of carbonic acid compete for the space
- When carbon dioxide is present, the hydrogen ions displace the oxygen on the haemoglobin
- More oxygen is released from oxyhaemoglobin into tissues
What does the pulmonary vein carry?
- Blood from lungs to heart
What is the aorta?
- The major artery leaving the heart
What do semi-lunar valves do?
- Prevent back flow of blood from arteries into ventricles
What do atrio ventricular valves do?
- Prevent back flow into atria
Which side of heart is thicker and why?
- Left because it pumps blood further
What is blood pressure?
- Pressure circulating blood on the blood vessels, indicates heart pumping ability and elasticity of blood vessels
- Top number is systolic blood pressure, highest level blood pressure reaches when heart beats
- Bottom number is systolic blood pressure, lowest level your blood pressure reaches as heart relaxes between beats
What is the cardiac cycle?
- The process of the cardiac muscle contraction and relaxation in one beat
What are the 3 phases of cardiac cycle?
1) Filling phase (DIASTOLE)
- Relaxation of both atria and ventricles
- Internal heart vol increases
- Blood flows into atria
- Arterial pressure is low
2) Atrial contraction (ATRIAL SYSTOLE)
- Small contraction pushes all blood into ventricles
- Stretches walls of ventricles ensuring they are full of blood
3) Ventricular contraction (VENTRICULAR SYSTOLE)
- Walls of ventricles contract, increasing pressure fast in up direction
- Semi-lunar valves open allowing blood out of heart
- Ventricle walls relax
- Blood pressure in arteries is high
What can myogenic muscle tissue do?
- Ininiate its own contraction