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-pharm Final > Autonomic nervous system (part 2) > Flashcards

Autonomic nervous system (part 2) Flashcards

1
Q

What drug class is donepezil?

A

Acetylcholine cholinesterase inhibitor

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2
Q

What is the action of donepezil?

A

Increases acetycholine in brain by inhibiting metabolism
Slows neural degradation of Alzheimer’s (55 weeks)

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3
Q

What are side effects of donepezil

A

Breathing problems: asthma, COPD and fainting
Sick sinus syndrome (heart disease), bradycardia, heart block
Trouble urinating, seizures

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4
Q

What do we monitor when administering donepezil?

A

CBC and bleed time

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5
Q

What are the contraindications of donepezil?

A

Cardiovascular and lung disease

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6
Q

When do we administer donepezil?

A

bedtime

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7
Q

How long does donepezil to peak?

A

3-8 hrs.

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8
Q

What drug class is sumatriptan in?

A

Triptans

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9
Q

What is the action of sumatriptan?

A

Binds to serotonin receptors to dilate cranial blood vessels

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10
Q

Why do we give sumatriptan?

A

Migraines, ha pain with or w/o aura

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11
Q

What are the se’s of sumatriptan?

A

CBS changes, dizzy, ha, anxiety
Aterations in bp, chest pain, shock

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12
Q

What is contraindicated in using sumatriptan?

A

Cerebro/ peripheral vascular disease
Older adults

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13
Q

What is a pt teaching for sumatriptan

A

No alcohol

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14
Q

When do we not administer sumatriptan?
Why?

A

Within 24 his of ergots
- risk of MI
- elevates BP

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15
Q

What drug class is diazepam in?

A

Benzodiazepines

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16
Q

What is the action of diazepam?

A

Enhances GABA

17
Q

Why must we be cautious when administering diazepam?

A
  • Schedule IV drug, highly addictive
18
Q

Why do we give diazepam

A

Antianxiety, hypnotic, and anticonvulsant reasons
( depression, psychosis, mania)
Prevents delerium/agitation in pts withdrawing from alcohol

19
Q

What are the side effects of diazepam?
How long do they take to present

A

CNS depressing, depressed mood with SI, decreased libido, bladder control
Restlessness
Take 2-3 days to present

20
Q

How many days does it take diazepam to reach a steady state?
What do we tell our pt

A

3- 7 days
Do not stop abruptly

-pharm Final (14 decks)

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