Lutheran Blood Group Flashcards

1
Q

First discovered in the serum of a patient lupus Erythematosus diffuses

A

Anti-Lu^a

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2
Q

The new antibody was named lutheran a misinterpretation of

A

Donor’s name Luteran

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3
Q

Lutheran antigens are NOT found in

A

Platelets
Monocytes
Granulocytes
Lymphocytes

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4
Q

Lutheran glycoprotein is widely distributes in tissues:

A

Brain
Lungs
Pancreas
Placenta
Skeletal Muscle
Hepatocytes (Fetal Hepatic Epithelial Cells)

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5
Q

Lutherans antigens are found on fetal RBC as early as 10 to 12 weeks but

A

POORLY DEVELOPED AT BIRTH

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6
Q
  • Poorly developed at birth
  • Do not reach until adult levels until age 15
A

Lu^a
Lu^b

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7
Q

Naturally occurring
React better at RT than 37 deg
Detected at IAT
May be IgM, IgG, IgA

A

Anti-Lu^a

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8
Q
  • IgG (IgG4) although IgM and IgA is noted
  • Reactive @37 deg cel DAT
  • made in Pregnancy or Transfusion
  • SHORTENED SURVIVAL OF TRANSFUSED CELLS and POSTTRANSFUSION JAUNDICE
A

Anti-Lu^b

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9
Q

Stronger agglutination when a Red Cell Antigen is expressed from HOMOZYGOUS GENES

A

Dosage Effect

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10
Q

Blood Group that exhibit Dosage Effect

A

Kidd & Duffy eats lots of M & Ns

(+) Lutheran

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