The Endocrine Pancreas- control of metabolism and biochemistry Flashcards
Energy intake (food) is controlled by the balance of which two hypothalamic centres?
Feeding centre
Satiety centre
What does the feeding centre do?
Promotes the feelings of hunger and drive to eat
What does the satiety centre do?
Promotes feeling of fullness by supressing the feeding centre
Which centre is sensitive to insulin?
Satiety centre
Which peptide hormone is released by fat stores and depresses feeding activity?
Leptin
What are the three classes of energy output?
Cellular work
Mechanical work
Heat loss
Metabolism?
Integration of all biochemical reactions in the body
What are the three elements of metabolism?
- extracting nutrients from food
- storing that energy
- utilising that energy for work
Anabolic pathways?
Higher bio :)))
Build up- synthesis of larger molecules from smaller ones
Often for storage purposes
Catabolic pathways?
Higher bio again :)))
Break down- degradation of large molecules into smaller
Releases energy in process
After eating, we enter an absorptive state. What does this mean?
Ingested nutrients supply the energy needs of the body and the excess is stored
Is the absorptive state an anabolic or catabolic phase?
Anabolic
Between meals and overnight, we enter a post-absorptive state where we rely on body stores to provide energy. Is this stage an anabolic or catabolic phase?
Catabolic
Most cells can use carbs, fats or protein for energy but which part of the body ca only use glucose?
Brain
Therefore, in the post-absorptive state, even though no new carb are gained, blood glucose conc. must remain sufficient to meet needs to brain.
What ay occur if there is low blood glucose?
Hypoglycaemia which can lead to coma and death