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[1ST YEAR] PH 105 - Pharmaceutical Analysis I (Lec) > PRELIM 02 - Neutralization Titration > Flashcards

PRELIM 02 - Neutralization Titration Flashcards

1
Q

Chemical processes in which an acid reacts with a base

A

Neutralization reaction

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2
Q

3 acid-base theories

A

Arrhenius concept, Brönsted-Lowry/Protonic concept, Lewis acid-base concept

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3
Q

Any substance capable of providing hydrogen ions (H+) in aqueous solution (Arrhenius concept)

A

Acid

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4
Q

Any substance capable of providing hydroxide ion (OH-) in aqueous solution (Arrhenius concept)

A

Base

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5
Q

Any substance capable of donating a proton (H+) in a chemical reaction (Brönsted-Lowry concept)

A

Acid

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6
Q

Any substance capable of accepting a proton (H+) in a chemical reaction (Brönsted-Lowry concept)

A

Base

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7
Q

Ionizes to produce a proton and the conjugate base of the acid

A

Brönsted acid

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8
Q

Are usually neutral molecules or anion

A

Brönsted bases

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9
Q

Species formed when a base accepts a proton

A

Conjugate acid

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10
Q

Any substance that is an electron acceptor (electron seeking, electrophilic) (Lewis acid-base concept)

A

Acid

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11
Q

Any substance that is an electron donor (nucleophilic) (Lewis acid-base concept)

A

Base

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12
Q

Logarithm of the reciprocal of the hydrogen ion activity

A

pH

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13
Q

An accurately weighed sample of a pure acid or base is titrated to a well-defined equivalence point

A

Neutralization titration

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14
Q

Are usually weak organic acids or bases in which the undissociated molecule has one color

A

Acid-base indicators

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15
Q

3 standard alkalimetric solutions

A

Sodium hydroxide, Potassium hydroxide, Barium hydroxide

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16
Q

Are used to sharpen up the color change

A

Mixed indicator

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17
Q

Method used for nitrogen determination

A

Kjeldahl method

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18
Q

4 classification of solvents

A

Amphiprotic, Aprotic, Basic, Inert solvent

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19
Q

Have both acidic and basic properties

A

Amphiprotic

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20
Q

Neither acidic nor basic

A

Aprotic

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21
Q

Most are extremely weak bases

A

Basic

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22
Q

Do not possess the acidic or basic properties

A

Inert solvents

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23
Q

A very weak proton acceptor

A

Acetic acid

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24
Q

Strongest of the common acids in acetic acid solution

A

Perchloric acid

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25
Q

Added to remove water from aqueous perchloric acid

A

Acetic anhydride

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26
Q

Titration medium commonly used in nonaqueous titration

A

Perchloric acid in acetic acid

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27
Q

Type of chemical reaction- preparation and standardization of 1N/0.5 N HCl

A

Neutralization

28
Q

Type of titration - preparation and standardization of 1N/0.5 N HCl

A

Direct titration

29
Q

Primary standard - preparation and standardization of 1N/0.5N HCl

A

Tromethamine

30
Q

Indicator - preparation and standardization of 1N/0.5 N HCl

A

Bromocresol green TS

31
Q

Endpoint/color transition - preparation and standardization of 1N/0.5N HCl

A

Blue to pale yellow

32
Q

Type of chemical reaction - preparation and standardization of 1N H2SO4

A

Neutralization

33
Q

Type of titration - preparation and standardization of 1N H2SO4

A

Direct titration

34
Q

Primary standard - preparation and standardization of 1N H2SO4

A

Tromethamine

35
Q

Indicator - preparation and standardization of 1N H2SO4

A

Bromocresol green TS

36
Q

Endpoint/color transition - preparation and standardization of 1N H2SO4

A

Blue to pale yellow

37
Q

Type of chemical reaction - preparation and standardization of 1N NaOH and 1N KOH

A

Neutralization

38
Q

Type of titration - preparation and standardization of 1N NaOH and 1N KOH

A

Direct titration

39
Q

Primary standard - preparation and standardization of 1N NaOH and 1N KOH

A

Potassium biphthalate

40
Q

Indicator - preparation and standardization of 1N NaOH and 1N KOH

A

Phenolphthalein TS

41
Q

Endpoint/color transition - preparation and standardization of 1N NaOH and 1N KOH

A

Colorless to permanent pink color

42
Q

Type of chemical reaction - assay of sodium bicarbonate, USP

A

Neutralization

43
Q

Type of titration - assay of sodium bicarbonate, USP

A

Direct titration

44
Q

Indicator - assay of sodium bicarbonate, USP

A

Methyl red TS

45
Q

Endpoint/color transition - assay of sodium bicarbonate, USP

A

Yellow to faint pink color

46
Q

Type of chemical reaction - assay of sodium hydroxide, NF

A

Neutralization

47
Q

Type of titration - assay of sodium hydroxide, NF

A

Direct titration

48
Q

Indicators - assay of sodium hydroxide, NF

A

Phenolphthalein TS, Methyl orange TS

49
Q

Endpoint/color transition - assay of sodium hydroxide, NF

A

Yellow to persistent pink color

50
Q

Type of chemical reaction - assay of sodium salicylate tablets, USP

A

Neutralization

51
Q

Type of titration - assay of sodium salicylate tablets, USP

A

Direct titration

52
Q

Indicator - assay of sodium salicylate tablets, USP

A

Bromophenol blue TS

53
Q

Endpoint/color transition - assay of sodium salicylate tablets, USP

A

Blue to permanent pale green color

54
Q

Type of chemical reaction - assay of zinc oxide, USP

A

Neutralization

55
Q

Type of titration - assay of zinc oxide, USP

A

Residual/back titration

56
Q

Indicator - assay of zinc oxide, USP

A

Methyl orange TS

57
Q

Endpoint/color transition - assay of zinc oxide, USP

A

Red to yellow

58
Q

Type of chemical reaction - assay of boric acid, NF

A

Neutralization

59
Q

Type of titration - assay of boric acid, NF

A

Direct titration

60
Q

Indicator - assay of boric acid, NF

A

Phenolphthalein TS

61
Q

Endpoint/color transition - assay of boric acid, NF

A

Colorless to pink color

62
Q

Type of chemical reaction - assay of aspirin, USP

A

Neutralization

63
Q

Type of titration - assay of aspirin, USP

A

Residual/back titration

64
Q

Indicator - assay of aspirin, USP

A

Phenolphthalein TS

65
Q

Endpoint/color transition - assay of aspirin, USP

A

Red to colorless

[1ST YEAR] PH 105 - Pharmaceutical Analysis I (Lec) (12 decks)

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