membrane potential Flashcards

1
Q

resting membrane potential

A

the inside- negative electrical potential that is normally recorded across all cell membranes

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2
Q

receptor potentials

A

the membrane potential change elicited in receptor neurons during sensory transduction

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3
Q

synaptic potentials

A

a membrane potential change generated by the action of a chemical transmitter agent
allow the transmission of info from one neuron to another

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4
Q

action potential

A

the electrical signal generated and conducted along axons by which info is conveyed from one place to another in the nervous system

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5
Q

depolarization

A

potential becomes less negative

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6
Q

hyperpolarization

A

potential become more negative

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7
Q

pressure is proportional to the

A

height

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8
Q

flow out of the bottom is proportional to

A

pressure/resistance of valve

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9
Q

3 features needed for neural signaling

A
  1. barrier (membrane)
  2. charge carrier (ions)
  3. gates and pumps (membrane proteins)
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10
Q

threshold potential

A

the level of membrane potential at which an action potential is generated

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11
Q

lipid bilayer

A

forms spontaneously
phospholipids - hydrophilic
non-polar lipid tails - hydrophobic

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12
Q

4 main ions involved in action potentials

A

cations: potassium, sodium, calcium
anions: chloride, protein molecules

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13
Q

active transporters

A

actively move ions into or out of cells against their conc gradient

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14
Q

ion channels

A

proteins that allow only certain kinds of ions to cross the membrane in the direction of their conc gradients

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15
Q

Nernst equation

A

Ek = (58/z) log (Ko/Ki)

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16
Q

Goldman-Hodgkin-Katz (GHK) equation

A

V = 58log (PkKo + PnaNao + Pcl Cli)/ (PkKi + PnaNai + PclClo)

17
Q

patch clamp

A

an extraordinarily sensitive voltage clamp method that permits the measurement of ionic currents flowing through individual ion channels

18
Q

current clamp

A

whole cell
we inject constant current and measure variable voltage

19
Q

voltage clamp

A

single channel
we inject variable current so as to maintain constant voltage

20
Q

in a current vs voltage plot the x intercept gives the

A

equilibrium potential