15&17 - Chronic Diseases Flashcards

(37 cards)

1
Q

What is the test in lower limb ischaemia?

A
  1. Buerger’s Test
  2. Elevate leg to 30 degress for 30-60 seconds
  3. Observe any colour change
  4. Colour change below 20 degrees indicates severe ischaemia
  5. Slow return of colour, or blueness indicates hyperaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CKD

- Seven medications groups?

A
  1. ACEi (protective)
  2. SGLT2
  3. Atorvastatin 20mg (CHD)
  4. Vit D/Colecalciferol
  5. EPO
  6. RRT
  7. Vaccination
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CKD

- Six safety-net flags?

A
  1. Oliguria
  2. Flank pain
  3. Pruritis
  4. Muscle pains
  5. Oedema
  6. Palpitations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the sick day rules for CKD and what qualifies?

A
  1. When vommitting and/or diarrhoea

2. Stop ACEi, NSAIDs, Diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What investigations are indicated in HTN for organ end-damage?

A
  1. Fundoscopy
  2. eGFR
  3. Bloods and ECG
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

HTN

- Three main drug groups

A
  1. ACEi/ARB
  2. CCB
  3. Thiazide-like diuretics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What safety-netting is indicated in HTN?

A
  1. Visual disturbance
  2. Sensory change
  3. BP > 180/90
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the criteria for Hyperlipidaemia?

A
  1. Total Cholesterol >5.18mmol/L
  2. LDL cholesterol > 2.49mmol/L
  3. HDL cholesterol <1.04 mmol/L
  4. Triglycerides > 1.7mmol/L
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Six hyperlipidaemia management options?

A
  1. Lifestyle modification
  2. 10% QRISK - Moderate intensity statin
    Atorvastatin 20mg
  3. High risk of ASCVD (atherosclerotic cardiovascular disease)
    Atorvastatin 40-80mg
  4. LDL-cholesterol remains >1.8mmol/L
    Ezetimibe 10mg PO
  5. LDL-c remains >1.8 at step 4
    Alirocumab 75-150mg (PCSK9 inhibitor - prevents LDLR antagonism)
  6. LDL-c >4.9 without DM and <75yo
    Colestyramine 4g PO (bile acid sequestrant)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Followup from commencing statin therapy?

A
  1. 3 Month lipid profile
    • Aim for 40% reduction
  2. Check CK levels
    - Watch for muscle pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tests for DM

A
  1. HbA1c
  2. Fasting glucose
  3. Fructosamine
  4. OGTT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DM 9 Processes of Care

A
  1. Screen before
    Retinopathy
    Peripheral vascular
    Albuminuria
  2. Lifestyle now
    Smoking
    BMI
    BP
  3. Monitor later
    Lipids
    HbA1c
    Creatinine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Statin Dosing in DM

A

QRISK >10%

Primary prevention - 20mg Atorvastatin
Secondary prevention - 80mg Atorvastatin + 75mg Aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DM with microvascular changes/microalbuminuria

- BP Target

A

DM target with changes:

  • 130/80
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DM Drugs and Targets

A

Metformin 500-2000mg
Liver
Muscles

  1. Gliclazide 40-320mg
    Pancreatic insulin (NB Hypos)
    Very potent - not for elderly
  2. GLP-1 eg Semaglutide 0.25-1mg once weekly
    Pancreatic action
  3. DPP-4
    Indirect/mild impact
    Sitagliptin 100mg oD
    Linagliptin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How to test the reversibility of a pulmonary disorder?

A
  1. Baseline spirometry
  2. Bronchodilation
    • Salbutamol (2 x 200mcg puffs)
      - Large volume spacer
  3. Pause for 30 minutes
  4. Repeat spirometry
    • FEV/FVC ration
17
Q

Example SABA inhalers?

A
  1. Salbutamol MDI (100mcg)
    • Ventolin
    • Salamol
    • Airomir
  2. Salbutamol DPI (200mcg)
    • Ventolin
  3. Terbutaline (500mcg)
    • Bricanyl
18
Q

ICS MDIs

A

ICS MDIs

  1. Clenil modulite
    • 50mcg Beclometasone
  2. QVAR
    • 50mcg Beclometasone
  3. Flixotide
    • 50 mcg Fluticasone
19
Q

ICS/LABAs

A

ICS/LABAs

  1. Seretide 250
    • 250mcg Fluticasone
    • 25mcg Salmeterol
  2. Symbicort 200
    • 200mcg Budesonide
    • 6 mcg Formoterol
  3. Fostair 200
    • 200mcg Beclometasone
    • 6 mcg Formoterol
20
Q

LABAs

A

Serevent MDI
- Salmeterol 25 mcg

Serevent Accuhaler
- Salmeterol 50 mcg

Formoterol Easyhaler
- 12 mcg formoterol

Oxis 6 turbohaler
- 6mcg formoterol

21
Q

LAMAs

A

LAMAs

  1. Spiriva Respimat SMI (soft mist)
    • 2.5 mcg Tiotropium bromide
  2. Spiriva MDI
    • 18 mcg Tiotropium Bromide
22
Q

Spacers

  1. Advantages
  2. Designs
A

Spacers

  1. Pros
    • Waste less
    • Fewer ADRs
  2. Designs
    • Volumatic
    • Aerochamber
23
Q

Asthma Prevention Plan

Three key components

A

Asthma Prevention Plan

  1. Everyday
  2. Exacerbation
  3. Attack
24
Q

Asthma Prevention Plan

  1. Everyday
A
  1. Everyday Asthma Prevention
    • Preventer inhaler regime
    • Reliever inhaler regime
    • Others
25
Asthma Prevention Plan 2. Exacerbation
2. Asthma Exacerbation plan - Symptom relief - Reliever use - Check PEFR levels - Step up medication
26
Asthma Prevention Plan 3. Attack
3. Asthma attacks response - Manage Sx - PEFR - Medications - Follow-up
27
Childhood asthma 1. DDs 2. Natural history
Childhood asthma 1. DDs - Viral wheeze - Foreign body 2. Natural history - 80% will outgrow - Atopy is RF for adult asthma
28
Asthma diagnosis follow up?
1. Lots of follow up (lots of information - RAPRIOP) - Reassure Reversible + not a lung pathology - Reliever Opens up muscle spasm - Preventer Reduces inflammation and mucus 2. Asthma nurse reviews 3. Medication reviews
29
COPD Rehab
COPD 1. Lecture on disease 2. Gym/exercise 3. CBT 4. Nicotine Patches COPD
30
COPD Doctor Role
COPD Doctor Role 1. Symptom management - eg. Inhalers 2. Slow progression - Eg. Smoking cessation
31
COPD Baseline History
1. Smoking - History - Current - Factors 2. Obesity - Risk Factor 3. Lifestyle - Occupation - ICE
32
Metformin 1. Indication 2. Dosing regimen
Metformin 1. Indication - 6.5% HbA1C for six months 2. Dosing regimen - 1 Week 500mg OD - 2 Weeks 500mg BD - 3 weeks tds/qds
33
GLP1 indications
GLP1 indications 1. BMI>30 2. CHD (Empa) 3. CKD (Dapa)
34
What are the stages of Buerger’s Test?
Buerger’s Test 1. Supine patient - Elevate legs to 45 - Palor = Ischaemia 2. Sit patient up - Hang legs at 90 flexion - Blue then red reveals post-hypoxic vasodilation
35
What is Buerger’s angle and what does it indicate?
Buerger’s Angle 1. 20 degrees 2. Indication of severe ischaemia
36
Limb ischaemia | - Dx
Limb ischaemia drugs - For prevention of vascular disease 1. Statin 2. Aspirin
37
Two broad causes of eosinophilia?
Eosinophilia? 1. Parasite 2. Asthma (responsive to steroids) - Allergies - Drug reactions