Fungus

Question 1

What is fungal cell wall made of?

Answer 1

Chitin & B-glucan

Question 2

What if fungal cell membrane made of?

Answer 2

Ergosterol

Question 3

What form do dimorphic fungi take inside the body?

Answer 3

Yeast form

Question 4

After metabolism in the body aflatoxins are turned into ……… which is a potent ………..

Answer 4

Epoxide ; Carcinogen

Question 5

Which aflatoxin induces mutation in p53?

Answer 5

B1

Question 6

Which foods is aflatoxin b1 found

Answer 6

Oil seeds (nuts & corns)

Question 7

T/F; superficial mycoses is identified by tissue destruction in the skin. Hair, & mucos membrane

Answer 7

F; destruction is not necessary

Question 8

What is the first indication of systemic mycoses ?

Answer 8

Failure to respond to Antibiotics?

Question 9

What serological test do use for mycoses?

Answer 9

ELISA

Question 10

Concentration of KOH in fungus microscopy?

Answer 10

10-20%

Question 11

What is calcofluor?

Answer 11

A fluorescent hydroxide that binds to the cell wall of fungi

Question 12

What stain do we use to for fungus identification under microscope?

Answer 12

India ink

Question 13

2 anti-contaminants used with sabouraud dextrose medium?

Answer 13

Chloramphenicol (bacteria)
Cyclohgeximide (saprophytic fungi)

Question 14

What disease does malassezia cause ?

Answer 14

Pityriasis versicolor

Question 15

What causes depigmentation in pityriasis versicolor?

Answer 15

Carboxylic acid released from malassezia

Question 16

What family of fungus does malassazia belong to ?

Answer 16

Yeast

Question 17

Descibe Malassazia furfur under microscope

Answer 17

Short thick septate hyphae
(Spaghetti & meatballs)

Question 18

Out of amphotracin B, nysatit, and azoles

Which are cidal & which are staric?

Answer 18

Polyenes are fungicidal
Azoles are fungistatic

Question 19

Give an example of subcutaneous mycoses & which fungus causes it

Answer 19

Madura foot by madurella mycetomatis