Skin facts

Question 1

Acne

Answer 1

during puberty especially with increased testosterone, blocked sebaceous glands

Question 2

Rosacea

Answer 2

Chronic high blood flow to BV in face and nose area

Question 3

Eczema

Answer 3

Dry, itchy inflamed skin mainly on elbows and knees

Question 4

Pruritus

Answer 4

Itch, usually from inflammatory mediator release from mast cells

Question 5

urticaria

Answer 5

Skin inflammation with raised wheals and bumps, many causes (exposure)

Question 6

Psoriasis

Answer 6

Autoimmune condition from hyperproliferation of keratinocytes

Question 7

Warts

Answer 7

Human papilloma virus,

Question 8

skin infections

Answer 8

bacterial
fungal
viral

Question 9

Skin glucocorticoids

Answer 9

-upregulate lipocortin which inhibits arachidonic acid factor production
-inhibits mitosis preventing skin growth
-causes vasoconstriction

Question 10

Retinoid action

Answer 10

RAR and RXR agonism modulates gene expression
-reduces sebaceous activity
-some anti-inflammatory

Question 11

Vit D

Answer 11

reduces proliferation and increases apoptosis of keratinocytes
-inhibits T cell activation