insulin secretion Flashcards

1
Q

where is insulin secreted from?

A

beta cells of islets of langerhans in the pancreas

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2
Q

what do alpha cells produce

A

glucagon

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3
Q

What initial step triggers insulin secretion

A

Blood glucose concentration is high, so more glucose enters a beta cells by facilitated diffusion

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4
Q

what happens when glucose enters the cell

A

More glucose in beta cells, causes the respiration to increase making more ATP

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5
Q

what did an increase in ATP cause

A

atp sensitive potassium(K+)channels close

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6
Q

what does the closure of k+ channels cause?

A

This means potassium ions can’t get through the membranes they build up inside the cell, Causing The plasma membrane to depolarise

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7
Q

depolarisation definition

A

The inside of the beta cell is less negative because there are more positively charged potassium ions inside the cell

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8
Q

what does depolarisation lead to

A

ca+ion channels open

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9
Q

what does the opening of the ca+ channel ions result in

A

influx of ca+ ions inside the cell

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10
Q

what doe a ca+ influx cause

A

signals insulin filled vesicle to merge with membrane(exocytosis) secretion of insulin

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