Vocab Flashcards
Monomer
Single units that make up biological molecules
Polymer
Chain of monomers
Proteins
Made of amino acids
Make up most of the body
4 main structures
Amino Acids
20 types
Differentiated by the R-groups
Form peptide bods to create polypeptides
Amino-R group-Carboxylic Acid
Hydrogen Bonding
Polar bonds between Hydrogen and Oxygen, Nitrogen or Fluorine
Responsible for properties of water
Cohesion
Ability of water to stick together, surface tension
Base
Solution with pH >7, more OH- ions
Buffer
Solution of water, a certain concentration of acid and same concentration of conjugate base. Ex. Carbonic Acid-Bicarbonate buffer
Lipid
Monomers with hydrocarbon tails that store energy
Saturated: No double bond, straight, solid
Unsaturated: Double bond, bent, liquid
Nucleic Acid
Genetic Material made of nucleotides
Includes phosphate group, sugar and nitrogenous base
Carbohydrates
Made of sugars
Sugars differ depending on the placement of the hydroxyl group
Used as energy
Monosaccharide
Disaccharide
Polysaccharide
Glucose, cellulose, glycogen
Polar
Uneven charges due to electronegativity
Neutral
Solution w/ pH of 7
DNA
Genetic material
RNA
Single strand, Uracil, used for protein synthesis
Dehydration Synthesis
Bringing together 2 molecules, creating a water molecule
Capillary Action
The ability of water to move up inside small tubes due to surface tension and interaction with polar surfaces
High Specific Heat Capacity
Takes a lot of energy to heat up water
Solvent
what the solute is dissolved into
ATP
energy currency, adenosine triphosphate
Releases last phosphate to release energy, creates ADP
pH
Concentration of H+. <7 acidic
7 neutral
>7 basic
Helicase
Unwinds DNA to begin replication
Starts at origin of replication
Is at fork of replication
Primase
Lays down RNA primers which signal DNA polymerase to begin replication
Lays more down on lagging strand
RNA primase
Similar to Primase
Longer RNA primer, different template
DNA polymerase
Replicates the DNA
Reads from 3-5, creates from 5-3
Uses phosphodiester bonds, pyrophosphate as a byproduct
3’ end
End with the 3 carbon
5’ end
End with the 5 carbon
Replication
Process of DNA being copied, semi-conservative
Guanine
Purine, pairs with Cytosine
Cytosine
Pyrimidine, pairs with Guanine
Gene
Sequence of DNA that codes for something, some code for proteins
mRNA
Carry codons to ribosomes for protein synthesis
Codon
Sequence of 3 nucleotides which code for an amino acid, found on mRNA
Initiation
First step in RNA synthesis
Initiation factors find promoter region to signal RNA polymerase
Helix
Curl/spiral found in DNA and RNA
DNA is a Double helix
Semi-conservative
In DNA replication, one strand is the original and the other is a new one. So, it is semi-conservative because it uses one of the original strands
Parent Strand
The original strand being used as a template
Daughter Strand
The new, complementary strand
Leading Strand
The strand created continuously because it runs in the 3-5 direction
Lagging Strand
Created in pieces because it runs in the 5-3 direction and the DNA polymerase must go back and create it in fragments
Origin of Replication
Place where Helicase binds and begins unwinding
Adenine
Purine, binds with Thymine or Uracil
Thymine
Pyrimidine, binds with adenosine
Genotype
Genetic expression of traits
tRNA
has anticodons and amino acids that it adds to the polypeptide chain inside the ribosome
Promoter Region
The sequence of nucleotides that signals the start of RNA synthesis. Has a common sequence called the consensus sequence
Elongation
Second stage of RNA synthesis
DNA strand is template/antisense strand
other is coding strand/sense
DNA
Nucleotides
Building block of DNA
Phosphate group, sugar (deoxyribose/ribose), nitrogenous base
Purine
Nitrogenous base with 2 rings
Pyrimidine
Nitrogenous base with 1 ring
Phosphodiester bond
Bonds that hold together the spine of DNA between phosphate groups and sugars.
DNA Gyrase
Creates negative supercoils to counteract the positive supercoils that are created when unwinding DNA
Okazaki fragments
The pieces through which the lagging strand is created
DNA ligase
Connects the Okazaki fragments
Uracil
Replacement for Thymine in RNA, pyrimidine
Phenotype
Physical representation of traits
rRNA
Makes up ribosomes along with proteins
Initiation factors
Move along DNA from Initiation point to find promoter region and signal RNA polymerase
Termination
The last part of RNA synthesis
RNA Polymerase reaches the termination sequence
Celera
Company that was rivaling the scientists in the Human Genome project
Said they could do it faster and cheaper
Used more inaccurate methods
Human Genome Project
Groups of scientists worldwide collaborated to sequence the first human genome
Cloning
Exact replication of DNA or an organism
GATTACA
Sci-Fi movie about DNA, and a man faking an identity using DNA
Biotechnology
Technology that uses biology to create products/machines
Genome
All genes in the human body
Sequencing
Process of creating a map of nucleotides in the correct order
CRISPR
Clustered Regularly Interspaced Short Palindromic Repeats
Used by bacteria as immune system
Used in gene editing
Gene Editing
Process of adding/removing certain genes to have a specific outcome using CRISPR
Ethics
Moral principals
Bioethics
Moral principles about biology, especially gene editing
Next-generation
Latest form of a product/technology
Disease
Condition that negatively affects an organism
Gene Therapy
Using CRISPR and gene editing to help treat genetic diseases
Controversial due to possible side effects
Metabolism
Process of breaking down nutrients/energy and turning them into what is useful for the body.
Radiation
Energy that comes from the sun, plants use it
Glucose
The main source of energy in the body, monosaccharide
Active Site
Site on enzymes where the substrate binds to
Has the same or a similar shape