Abdominal Vivas Flashcards
What causes ascites with a SAAG >11?
Liver: Cirrhosis, alcoholic hepatitis, acute liver failure, liver mets
Cardiac: Right HF, constrictive pericarditis
Budd-chiari syndrome, portal vein thrombosis
What is indicated by a high SAAG >11?
Transudate
Portal HTN
What causes ascites with a SAAG <11?
Hypoalbuminaemia: nephrotic syndrome
Malignancy: peritoneal carcinoma
Tuberculous peritonitis
Pancreatitis
Bowel obstruction
What is indicated by a low SAAG <11?
Ascitic fluid is an exudate
5 complications of ascites
SBP
Hepatorenal syndrome
Malnutrition
Pleural effusion
GI bleed
What is SBP? How is it diagnosed? What is the most common organism involved?
Bacterial infection of ascitic fluid
Paracentesis: neutrophils >250 cells/ul
E.coli
Management of SBP
IV Cefotaxime
SBP prophylaxis
Ciprofloxacin PO for those with cirrhosis + ascites with ascitic protein ,<15
or if have had an episode of SBP
Management of ascites
Reduce dietary sodium
Fluid restrict
Aldosterone antagonists: Spironolactone
Therapeutic abdominal paracentesis (requires albumin cover)
Transjugular intrahepatic portosystemic shunt (TIPS)
What is a transjugular intrahepatic portosystemic shunt?
Procedure creates internal ‘bypass’ between portal vein + hepatic vein
List 4 indications for a TIPS procedure?
Acute variceal bleeding where other interventions have failed
Recurrent variceal bleeding
Refractory ascites
Hepatorenal syndrome
What is hepatorenal syndrome?
‘Functional’ kidney impairment due to severe renal vasoconstriction in patients with cirrhosis
Reduction in renal blood flow + GFR
4 absolute CI to laparoscopic surgery
Haemodynamic instability/ shock
Raised ICP
Acute intestinal obstruction with dilated bowel loops (> 4 cm)
Uncorrected coagulopathy
Indications for laparoscopic surgery
Diagnostic: appendicitis, PID, endometriosis
Therapeutic: Appendicectomy, cholecystectomy, hernia repair, hysterectomy, fibroidectomy
4 Benefits of laparoscopy
Faster recovery time + shorter stay
Less pain
Less risk of infection
Smaller scars
5 Complications of laparoscopy
Risks of anaesthetic
Vasovagal bradycardia in response to abdominal distension
Extra-peritoneal gas insufflation: surgical emphysema
Injury to GIT
Injury to blood vessels e.g. common iliacs, deep inferior epigastric artery
Which patient should be assessed for renal transplant?
All with end stage renal failure (GFR <15) or CKD stage 4 with progressive disease (GFR 15-29)
List 5 absolute contraindications to renal transplant
Untreated malignancy
Active infection
Untreated HIV/ AIDS
Condition with life expectancy <2y
Malignant melanoma within past 5y
Renal transplant immunosuppression regime
Initial: ciclosporin/ tacrolimus with a monoclonal antibody (Basilximab)
Maintenance: ciclosporin/ tacrolimus with MMF or Sirolimus
Add steroids if >1 steroid responsive acute rejection episode
Graft survival for renal transplants
Cadaveric: 1y= 90%, 10y = 60%
Living-donor: 1y= 95%, 10y= 70%
5 post-op problems of renal transplant
ATN of graft
Vascular thrombosis
Ureteric leaks
UTI
Delayed graft function (need for dialysis within 1st week)
Describe hyper acute rejection of a renal transplant
Mins- hours
Due to pre-existing Abs to ABO/ HLA
Widespread thrombosis of graft vessels + ischaemia + necrosis
Graft MUST be removed