lect 1 Flashcards

1
Q

what is misuse?

A

the use of any prescribed medication for non prescribed reasons:

-recreational use
-self treating acute pain
-to give to someone else
-sell
addiction

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2
Q

what is abuse?

A

a condition characterized by a self destructive pattern of using a substance that leads to a significant problems and distress

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3
Q

what is dependence

A

-characterized by SX of tolerance and withdrawal

person needs more and more of something to get the same effect (tolerance), and they experience unpleasant symptoms when they stop using it (withdrawal).

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4
Q

tolerance?

withdrawal?

A

T: decrease response to a drug used repeatedly

W: unpleasant physical and mental effects that a person experiences after they stop using substance

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5
Q

what is addiction?

A

marked by a change if behavior caused by biochemical changes in the brain after continued substance abuse.

-becomes the main priority of the addict regardless of the harm they cause to themselves or others

-makes them act irrational

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6
Q

substance use disorder is?

A

abuse, dependence and addiction

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7
Q

Substance Use disorder DSM-5

A

->2 in the last 12 months

-hazardous use
-social/interpersonal problems
-neglected major roles to use
-withdrawal
-tolerance
-used larger amounts for longer periods of time
-repeated attempts to control or quit
-much time spent using
-physical or psychological problems related to use
-activities given up to use
-cravings

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8
Q

severity of disorder

2-3 criteria:

4-5 criteria:

> 6 criteria:

A

2-3 criteria: mild

4-5 criteria: mod

> 6 criteria: severe

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9
Q

8 most common substances of abuse

A

-opioid
-alcohol
-tobacco
-cannabis
-stimulant
-hallucinogen
-inhalant
-sedative, hyponotic

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10
Q

the # of criteria @ initial diagnosis is INVERSLEY proportional to success of rehab

A
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11
Q

opioid misuse statistics:

A

11 million misuse opioids yearly

52 million misuse it lifetime

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12
Q

screening for opioid:

A

-revised screener and opioid assessment for pts w pain (SOAPP-R):

> 18 is an increase risk for opioid misuse
-best sensitivity

Opioid risk tool: MC used
-4-7 mod risk
->7 high risk
-most commonly used
-takesgender differences into account

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13
Q

in opioid risk tool: the males and females differ?

A

-males who do Opi has an assoc. of alcohol and illegal drugs

-females :16-45
-preadolescent sexual abuse

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14
Q

Questions to ask for OPI pts:

A

-use of OPI
-other substances
-family hx
-psychiatric
-specific diagnoses (hep B)
-nicotine dependence
-unexplained pain

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15
Q

Opioid DSM-5

A

2 of the following occur w/in 12 months that lead to impairment or distress:

-opioid taken in larger amounts or over long period of time

-desire to cut down
-much time using opioid
-craving/urge
-failure to fulfill obligations
-continues use despite the problems of opioid use
-recreational use caused social activities up
-tolerance
-withdrawal

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16
Q

do not prescribe OPI:

A

-if pt has opi use disorder
-pre existing substance abuse
-hx of suicide attempt
-already on opi for chronic pain
-hx of overdose

17
Q

proper use of opi per cdc

A

-check database first
-NSAID first since its = to opi effects for pain

-if nsaids dont help, opi is second line
NO MORE THAN 3-7 days

18
Q

calculating MME categories:

A

safe: < 50 MME
borderline: 90 MME
tolerant: >200 MME

overdose is > 100 mme is 9x taking 20 MME

19
Q

50% of pts on opi for 90 days develop opi disorder

A
20
Q

what is the proper use of opi per cdc

A

-chronic pain
-terminal conditions
-hospice

any other chronic condition STOP

21
Q

how to stop opi :

what meds to use to get them off opi?

A

fast taper: if not appropiately used

slow taper: pts with long term use or w tolerance

medications:
naltrexone-opiod blocker [DONT USE ifpt was using opi in the LAST 7 days]

22
Q

treatin opioid withdrawal:

sweats, tremor, anxiety, htn:
insomnia, anxiety, restlessness:
fever, pain:
nausea and vomiting:
diarrhea:
muscle spasm:
dyspepsia:

A

sweats, tremor, anxiety, htn: clonindine (3x)

insomnia, anxiety, restlessness: : diphendramine, hydroxyzine

fever, pain: NSAID / acetaminophen

nausea and vomiting: promethazine, metaclopramide

diarrhea: loperamide

muscle spasm: methocarbamol

dyspepsia: symptomatic measure

23
Q

alcohol misuse:

A

drinking alot that causes harm to n others

drinking underage or pregnant

24
Q

binge drinking

A

NIAAA defines it as a:
-pattern of drinking that brings BAC to 0.08 g/dl or higher

-woman consumes 4 or more drinks– 2 hrs
-man 5 drinks or more –> 2 hrs

25
Q

binge drinking per SAMHSA:

A

-consuming more than 5 or more drinks in the same occasion or atleast one day a month

26
Q

high intensity drinking

A

consumption of 2 or more times gender specific thresholds for binge drinking which is to say 10 or more standard drinks for males and 8 or more for females

-high intensity drinking is consistent at binge levels II and III.

27
Q

alcohol stats for :

ppl in ED visits bc of alcohol:
traffic accidents:
cost national:
pregnant women:

fetal alcohol spectrum disorders:

A

ppl in ED visits bc of alcohol: 10.2%
traffic accidents: 18.5%
cost national: 249 billion
pregnant women: 9.5%

fetal alcohol spectrum disorders:1-5% 6000 first graders

28
Q

DSM-5 Alcohol Use Order

A

-a maladaptive pattern substance leading to impairment by 2 + in the 12 month period:
-alcohol often taken in longer period of times or larger amts.

-persistent desire to cut down
-great amount of time in activities getting alcohol or recovering
-failure to do activities
-craving, desire or urge for alcohol
-recreational use caused social activities up
-tolerance
-withdrawal

29
Q

Substance use disorder:
severity of disorder

A

-2-3: mild substance dis.
-4-5: mod.
>=6: severe

severe alcohol use order= alcoholism

30
Q

alcohol use disorder TX:

A

-pt must recognized he has a problem
-clinician recognizes severity

MHM: negotiate

31
Q

Screening tools for Alcohol use disorder:

A

-CAGE- specific high
-AUDIT [highest sens]
women>4 ;m>8
-AUDIT-C [3 ?s]

32
Q

CAGE:

A

-cut down
-annoyed
-guilty
-eye opener

1: low risk
2-3: high susp.
4: diagnosis for alcoholism

33
Q

Alcohol brief intervention:

A

enhance motivation instead of blaming, evoke a change in a person, trusting environment [no judges],

34
Q

outpatient rehabilitation:

A

-pts who have severe alcohol use or cant decrease

-includes psychotherapy
- or group therapy

35
Q

inpatient rehab

psychotherapy:

A

-for severe/dependent alcohol pts and those with comorbid psychoactive, abuse problems.

-teach pts. to avoid circumstances that could lead to drinking

36
Q

Disulfiram:

ABYSMAL COMPLIANCE- pt is non adherent n fails to take tx

A

interferes w ACETALDEHYDE accumulates

drinking alcohol w/in 12 hrs taken disulfiram:

-vasodilation, flushing, sweating, tachy

disulfiram purposely causes unpleasant side effects if alcohol is consumed.

37
Q

Naltrexone: opioid antagonist

Gaba

clonindine:dec htn n tachy withdrawal

A

decreases relapse rate, must be off opioid 7 days,