Connective Tissue Disorder Flashcards

1
Q

Systemic Lupus Erythematosus Cause

A
  • Autoimmune
  • +Ve serum antinuclear antibodies (ANA)
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2
Q

Systemic Lupus Erythematosus
Presentation

A

Joints: arthritis,effusion
Skin:
- Butterfly rash
- localized erythema and edema
- alopecia (loss of hair)
- photosensitive
- mucosal ulcer
- Raynaud’s

Blood: formation of DVT,PE, low blood cell count

Lungs: pleuritis

Kidney: impaired kidney function

CNS: seizure, transverse myelitis, CVA

Hear:inflammation and valve dysfunction

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3
Q

Scleroderma

A
  • fibrous degeneration of connective tissue of the skin, lungs and internal organs
  • lead to:
    Joint contractures
    pulmonary fibrosis
    GI dysmotility
    tight, drawn skin
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4
Q

Ehlers-danlos

A

Cause:
- Genetic
- defect in collagen synthesis

S&S:
- associated with hypermobility and can affect the cardiac muscle

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5
Q

Larsen syndrome

A

Cause:
- Genetic

S&S
- Prominent forehead
- Widespread eyes
- Multiple joint dislocation
- Foot deformities

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6
Q

Marfan’s syndrome

A

Cause:
- Genetic disease
- lack of fibrillin

S&S:
- long hands
- loose joints, scoliosis
- involves the heart and eyes

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