Cell cycle (2) (abnormal) Flashcards

1
Q

What is altered during oral carcinogenesis?

A

cellular responses to metabolic stress or genomic damage through p53 and related pathways that block cell cycle progression are also altered during oral carcinogenesis. In addition, new pathways and cell cycle regulatory proteins, such as p12DOC-1 are being discovered

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2
Q

what is the multistep process of oral carcinogenesis likely to involve?

A

functional alteration of cell cycle regulatory members combined with escape from cellular senescence and apoptotic signaling pathways

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3
Q

what is genomics?

A

interdisciplinary field of biology focusing on the structure, function, Evolution, mapping and editing of genomes. A genome is an organisms complete set of DNA-it includes all the genes

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