Additive Effects

Question 1

methylene blue

Answer 1

potent MAOI

Question 2

what does methylene blue interact with

Answer 2

Serotonin reuptake inhibitors (selective and nonselective, SSI/SSRI) and SNRI (serotonin-Norepinephrine)

Question 3

what can induce serotonin toxicity

Answer 3

methylene blue

Question 4

caution with blue arm syndrome

Answer 4

methylene blue

Question 5

serotonin toxicity

Answer 5

Question 6

fluorescein dye use

Answer 6

Used to Visualize ureters during cystoscopy

Question 7

fluorescein dye dose

Answer 7

50-100 mg IV (100 mg/ml)
takes ~5 min to work

Question 8

fluorescein dye precautions

Answer 8

bronchial asthma, avoid extravastion

Question 9

indigo carmine

Answer 9

Inactive blue dye routinely given IV during urologic and gynecologic procedures to localize the ureteral orifices

Question 10

indigo carmine dose

Answer 10

5 mL (8mg/cc)

Question 11

indigo carmine can cause

Answer 11

hypertension due to increased PVR with increased HR

Increased BP with reflex decrease in HR

Question 12

indigo carmine can rarely cause

Answer 12

hypotension, cardiac arrest, and cerebral ischemia

Question 13

indocyanine green used for

Answer 13

highlighting structures in robotic surgery

tissue blood flow for reconstructive/ plastic surgeryi

Question 14

indocyanine green peak spectral absorption

Answer 14

at about 800 nmw

Question 15

how should indocyanine green be reconstituted

Answer 15

10 mL sterile H2O

Question 16

indocyanine green dose

Answer 16

2.5 mg given with 10mL rapid bolus flush

Question 17

how long does it take indocyanine green to be visible

Answer 17

about 30 s.