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Applied Anatomic Pathology > Lung > Flashcards

Lung Flashcards

1
Q

D.

A

Apical

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2
Q

E.

A

Posterior

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3
Q

F.

A

Anterior

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4
Q

G.

A

Medial

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5
Q

H.

A

Lateral

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6
Q

I.

A

Superior

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7
Q

J.

A

Posterior Basal

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8
Q

K.

A

Lateral Basal

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9
Q

L.

A

Anterior Basal

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10
Q

O.

A

Apico-Posterior

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11
Q

P.

A

Anterior

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12
Q

Q.

A

Superior Lingular

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13
Q

R.

A

Inferior Lingular

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14
Q

S.

A

Superior

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15
Q

T.

A

Lateral Basal

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16
Q

U.

A

Posterior Basal

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17
Q

V.

A

Anterior Basal

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18
Q

what is the most frequently diagnosed major cancer and most common cause of cancer mortality worldwide

A

lung cancer

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19
Q

what is the most common type of lung cancer

A

adenocarcinoma - a type of non-small cell lung cancer

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20
Q

what is the second most common type of lung cancer

A

squamous cell carcinoma - a type of non-small cell lung cancer

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21
Q

which type of lung cancer tends to be more peripheral

A

adenocarcinoma

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22
Q

which type of lung cancer tends to be more central

A

squamous cell carcinoma

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23
Q

what is mucoviscidosis

A

cystic fibrosis - disorder of iron transport that leads to viscous secretions that cause obstructions in the lung

24
Q

what is the most common lethal genetic disease that affects Caucasians

A

mucoviscidosis (aka cystic fibrosis)

25
Q

what are the four types of emphysema

A

centriacinar
panacinar
paraseptal
irregular

26
Q

which type of emphysema is most common (smokers)

A

centriacinar

27
Q

what is bulbous emphysema

A

emphysema that includes large sub-pleural blebs near apex of lung

28
Q

what is idiopathic pulmonary fibrosis

A

progressive interstitial pulmonary fibrosis and respiratory failure
grossly shows a cobblestone pleural surface

29
Q

which condition has a cobblestone pleural surface and honeycomb pattern radiologically

A

idiopathic pulmonary fibrosis

30
Q

what is the difference between emphysema and idiopathic pulmonary fibrosis

A

emphysema: enlargement of airspaces
IPF: fibrosis destroys airspaces

31
Q

what is emphysema

A

irreversible enlargement of the airspaces distal to the terminal bronchiole

32
Q

what are three examples of pneumoconiosis

A

anthracosis
silicosis
asbestosis

33
Q

what is the most prevalent chronic occupational disease in the world

A

silicosis

34
Q

what can asbestos cause

A

mesothelioma

35
Q

what is sarcoidosis

A

granulomatous disease which leads to bilateral hilarity lymphadenopathy, parenchymal lung involvement, and granulomas (multinucleated giant cells)

36
Q

what is the leading cause of death worldwide

A

tuberculosis

37
Q

HIV infection is associated with an increase risk of _______

A

TB

38
Q

what is a Ghon complex

A

parenchymal lung lesion and nodal involvement caused by TB

39
Q

which chemical is most commonly used to disinfect from TB

A

bleach

40
Q

“coin lesions” are associated with which condition

A

hamartomas

41
Q

what are the two main subtypes of lung adenocarcinoma

A

mucinous vs non-mucinous

42
Q

what are the 5 basic histologic patterns of non-mucinous lung adenocarcinoma

A

acinar
papillary
micropapillary
lepidic
solid

43
Q

what is the lepidic variant of lung adenocarcinoma

A

cells appear to be crawling as they’re growing along the surface of the alveolar septa

44
Q

what is large cell carcinoma

A

a type of non-small cell lung cancer that is diagnosis by exclusion

45
Q

what is small cell carcinoma

A

includes neuroendocrine tumors and carcinoids
usually adjacent to bronchi

46
Q

should you weigh a lung specimen

A

yes, before it has been fixed

47
Q

which ink color should you avoid with lung specimens

A

black because it may look like anthracotic pigment

48
Q

lung wedges are most commonly which type of cancer

A

adenocarcinoma since it is mostly peripheral

49
Q

which sections should you submit in a lung wedge specimen

A

mass
mass to nearest margin
shave of margin
mass to pleura
normal

50
Q

what is an important measurement in a lung specimen

A

bronchus measurement to show if its patent

51
Q

how should you open a lung for squamous cell

A

along open bronchial airway

52
Q

how should you open a lung for adenocarcinoma

A

serially section, longest axis of tumor

53
Q

what sections should you submit for a lobectomy

A

bronchovascular/hilar margin
mass
mass to pleura
mass to bronchus
mass to normal
normal
all lymph nodes

54
Q

what is the most important factor when staging lung cancer

A

tumor size

55
Q

which stage involves the pleura

A

T2 and above

Applied Anatomic Pathology (17 decks)

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