neuropato Flashcards
What is the primary mechanism leading to an ischemic stroke?
Occlusion of a cerebral artery by a thrombus or embolus
What is the primary reason for the increased risk of foot ulcers in patients with diabetic neuropathy?
Decreased sensation leading to unrecognized injury.
The symptom most indicative of a stroke affecting the cerebellum is:
Ataxia
What is the role of alpha-synuclein in the pathogenesis of Parkinson’s Disease?
Misfolds and aggregates, leading to neuronal death
Lewy bodies, a hallmark of Parkinson’s Disease, are primarily composed of which protein?
Alpha-synuclein
The pathophysiological change not typically associated with diabetic neuropathy is:
Increased nerve growth factor (NGF) production.
A symptom of autonomic neuropathy is:
Gastroparesis leading to nausea, vomiting, and bloating
The mechanism primarily involved in the pathogenesis of diabetic neuropathy is:
Accumulation of AGEs in nerve tissues
In the context of diabetic neuropathy, what role does oxidative stress play in neuronal damage?
It leads to the accumulation of reactive oxygen species (ROS), damaging neuronal cells
The risk of developing diabetic neuropathy can be reduced by controlling hyperglycemia. What is the proposed mechanism for this effect?
Reduction in oxidative stress and inflammation in nerve tissues
Which imaging technique is most commonly used for the initial assessment of a suspected stroke?
CT scan
How does the presence of Lewy bodies in various parts of the brain contribute to the range of symptoms experienced by Parkinson’s Disease patients?
By contributing to the loss of neurons across different brain regions, affecting both motor and non-motor functions
The correct statement about Transient Ischemic Attack (TIA) is:
It is a strong predictor for future strokes.
The motor symptoms observed in Parkinson’s Disease are primarily due to:
Degeneration of dopaminergic neurons in the substantia nigra.
The symptom not typically associated with Parkinson’s Disease is:
Hyperreflexia.
