Drugs

Question 1

Topirimate, Primidone, Phenytoin, Phenobarbital, Oxcarbazepine, Carbamazepine are what?

Answer 1

Enzyme inducing antiepileptics

Question 2

Modafanil is an enzyme inducer used to treat?

Answer 2

Narcolepsy/self sourced to improve alertness

Question 3

Nevirapine Efavirenz Ritonavir are ART and what?

Answer 3

Enzyme inducers

Question 4

Rifabutin and Rifampicin treat TB and are what?

Answer 4

Potent enzyme inducers

Question 5

What are warfarin, ace inhibitors, aldosterone antagonists?

Answer 5

Teratogenic medications used in cardiac disease

Question 6

Is Lamotrigine an enzyme inducer?

Answer 6

No. You can use implant therefore

Desogestrel might increase levels of lamotrigine and SE

Question 7

What are contraindications to lidocaine?

Answer 7

Complete heart block
Hypovolaemia
Known sensitivity
Hydroxybenxoate allergy

Question 8

What drugs Interact with lidocaine?

Answer 8

Beta blockers, cimetedine, antiviral agents, noradrenaline increase action of lidocaine

QT prolonging eg antipsychotics increase risk of Ventricular Tachycardia

Low K+ decrease action lidocaine

Crosses placenta-so just consider risk v benefit

Question 9

Can you use sodium valproate with implant?

Answer 9

Yes -
implant highly effective and sodium V not an enzyme inducer but teratogenic