NEOPLASIA Flashcards

1
Q

Define Neoplasia?

A

Slide 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define Neoplasm?

A

Slide 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Persistent of tumor results from?

A

Slide 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Differentiate between cancer and tumor

A

Slide 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tumors are clonal. Why?

A

Slide 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tumor depends on the host for?

A

Slide 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name and explain the Two basic components of tumors?

A

Slide 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name four basic components of tumors?

A

Slide 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Differentiate between benign and malignant tumors

A

Slide 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Define cell differentiation?

A

Slide 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Define Anaplasia?

A

Slide 17
10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Define Parenchyma and Stroma?

A

Slide 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tumors can be differentiated on the basis of?

A

Slide 9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Define Dysplasia?

A

Slide 12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Define Dysplasia?

A

Slide 12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Define Local invasion and Metsastasis

A

Slide 15

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Define Papillary Cystadenoma

A

Slide 29

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Tumors arising from mesenchymal tissue are known as? give 2 examples?

A

Slide 30

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tumors that started from epithelial cell called? Give example

A

Slide 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Define Adenocarcinoma?

A

Slide 32

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is a mixed tumor?

A

Slide 33

22
Q

Mixed tumors are monoclonal, what does this mean?

A

Slide 33

23
Q

Mixed tumour contains representative of a single germ layer, give examples of theses?

A

Pleomorphic adenoma
Slide 33

24
Q

Teratomas resemblance normal derivatives of?

A

More than one germ layer, arises from totipotent cells
Slide 33

25
Q

Define Harmatoma?

A

Malformation of a mass of disorganized but matured specialized cells or tissues indiginous to a particular
Site eg Odontoma
Slide 35

26
Q

Define Choristoma? Nomenclature of Misnormer

A

Slide 35

27
Q

List the role of factors that lead to the pathogenesis of neoplasm? [5]

A

Slide 36

28
Q

Most cancers are ———————– butsome are ———————-?[2]

A
  1. Sporadic (random, isolated, scattered)
  2. Familial
29
Q

What are the features that characterized familial cancers?

A

Slide 36

30
Q

Explain Genetic predisposition to cancer?

A

Slide 38

31
Q

Explain Age as a predisposing factor to developing CA?

A

Slide 39

32
Q

List CA that affects children? [6]

A

WRRONL
Slide 40

33
Q

How does the environment lead to development of carcinomas?

A

Slide 41-42

34
Q

Explain how acquired factors predispose people to Neoplasm?

A

Slide 43

35
Q

Explain the acquired predisposing factors to neoplasm?

A

Slide 43

36
Q

Define a precursor lesion

A

Slide 44

37
Q

Differentiate between precursor lesion and precursor condition table

A

Slide 44

38
Q

Deficiency of —————– increase risk of cancer?

A
  1. T-cell immunity
    Slide 44
39
Q

Discuss cellular and molecular Hallmarks of CAancer? [8]

A

Slide 46

40
Q

Define carcinogenic?

A

Slide 48

41
Q

Genetic change in carcinogenesis can be due? [3]

A

Slide 48

42
Q

Define genetic hypothesis?

A

Slide 49

43
Q

What are the targets for cancer causing mutations (regulatory) ?

A

Four classes
Slide 50

44
Q

Discuss Proto-oncogene?

A

Slide 51

45
Q

Explain the MoA of Proto-oncogene? [4]

A

Slide 51

46
Q

Anti cancer drugs target?

A

Oncogenes
Slide 52

47
Q

Genetic mechanisms associated with oncogene activation are? [4]

A

Slide52

48
Q

What does tumo7r suppressor genes need?

A
  1. Both alleles to be damaged for transformation to occur
49
Q

Dicuse the function of Tumour suppressor genes?

A

Slide 53

50
Q

Etiology over cancer: carcinogenic agents? [3]

A

Slide 55