Lecture 8 - Sex and the brain Flashcards

1
Q

What is genotype?

A

the full set of genes that an organism possesses, different genes are organised into chromosomes

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2
Q

How many chromosomes does an individual have?

A
  • 46
  • 23 from mother
  • 23 from father
  • a female has 2 X chromosomes and a male has 1 X and 1 Y
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3
Q

Sex hormones?

A
  • testosterone
  • progesterone
  • released in different proportions by both male and female reproductive organs
  • all hormones come from cholesterol
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4
Q

What are the 3 things we are a product of?

A
  1. genotype (XX or XY)
  2. action of sex hormones
  3. proportion of sex hormones
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5
Q

The male and female brain?

A
  • certain regions of the brain are ‘sexually dimorphic’
  • the pre-optic nucleus is bigger in adult males and is related to testosterone levels and sexual activity in males
  • the ventromedial nucleus of the hypothalalmus is involved in female sexual behaviour etc.
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6
Q

Genetic mutations that affect sexual identity?

A
  • usually the genotype and phenotype sex of an individual are aligned
  • however there are a variety of genetic mutations that result in an ambiguous sexual phenotype e.g.
    -> Turner’s syndrome
    -> Congenital adrenal hyperplasia
    -> Androgen insensitivity syndrome
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7
Q

Female sexual behaviour in rats?

A
  • mediated by the ventromedial region of the hypothalamus
  • dependent on estradiol & progesterone
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8
Q

Male sexual behaviour in rats?

A
  • mediated by the pre optic area of the hypothalamus
  • dependent on testosterone
  • oxytocin release plays a role in pair bonding
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9
Q

Women’s facial attractiveness and the fertile period?

A
  • faces in fertile window and luteal phase are ranked as more attractive compared to faces in the follicular phase
  • estradiol produces changes in face attractiveness
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10
Q

What is the amygdala’s involvement in human sexual motivation?

A
  • viewing erotic movies caused activity in the amygdala for men and women
  • amygdala volume correlated with sexual interest in epilepsy patients who underwent temporal resection
  • stimulation of amygdala in an epilepsy patient elicited sexual experience related sensations
  • potentially related to amygdala’s processing of emotional arousal
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11
Q

What is the role of the frontal lobe in sexual behaviour?

A
  • amygdala and hypothalamus are both involved in sexual motivation and sexual behaviour
  • lesions to frontal lobe cause:
    -> loss of inhibition about sexual behaviour
    -> erotomania = conditon in which people believe that another person is in love with them
  • lesions to the dorsolateral prefrontal cortex (DLPFC) = aggressive sexual behaviour
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12
Q

What happens when the DLPFC is stimulated?

A
  • p’s reported less intent to commit physical/ sexual assault
  • p’s reported an increase in immorality of the act
  • the increase in immorality rating explained the decrease in intent
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13
Q

Sexual reward?

A
  • successful completion of sexual behaviour (orgasm) is accompanied by a reward
    -> dopamine release
    -> relaxation due to oxytocin release
  • oxytocin may aid in pair bonding and is said to be involved in mother-infant bonds
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14
Q

Differences in cognitive ability between sexes?

A
  • women perform better on tests of verbal fluency
  • men perform better on tests of spatial reasoning
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15
Q

What are pheromones?

A
  • they carry messages from 1 animal to the other and affect reproductive behaviour
  • detected by olfactory receptors
  • processed by the vomeronasal organ which activate the amygdala and the hypothalamus
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16
Q

What to pheromones lead to in rats?

A
  • acceleration of puberty when housed with a male
  • restarting the esters cycle of female rats exposed to odour of a male
  • termination of early pregnancy when exposed to a novel male
17
Q

What can pheromones lead to in humans?

A
  • synchronisation of menstrual cycles
  • higher pleasantness ratings of odour from females during the fertile period
  • pheromones are detected by the normal olfactory system in humans
18
Q

Savic and Lindström (2008)?

A
  • wanted to see whether homosexual men and women show sex atypical symmetry and connectivity
  • results regarding symmetry:
    -> homosexual women and heterosexual men show asymmetrical brains
    -> heterosexual women and homosexual men show more symmetry
  • results regarding amygdala connectivity:
    -> similar in heterosexual men and homosexual women
    -> sensorimotor systems and striatum regulating an action-related response
    -> similar in homosexual men and heterosexual women
    -> regions of the limbic system regulating stress, mood & anxiety related response