Alzheimer Disease Flashcards
1
Q
What drugs are used to treat Alzheimer Disease and Dementia?
A
Centrally acting Acetylcholinesterase Inhibitors
- donepezil
- rivastigmine
N-Methyl-D-Aspartate (NMDA) Receptor Antagonist
- memantine
2
Q
What do Centrally acting Acetylcholinesterase Inhibitors treat?
A
- Alzheimer Disease
- Dementia
3
Q
What are some Centrally acting Acetylcholinesterase Inhibitors?
A
- donepezil
- rivastigmine
4
Q
What are common adverse effects of Centrally acting Acetylcholinesterase Inhibitors?
A
- GI symptoms
- Dizziness
- Bronchoconstriction
- Symptomatic bradycardia
- SLUDGE’M and the Killer B’s
5
Q
When should you administer Centrally acting Acetylcholinesterase Inhibitors?
A
bedtime without regard to food
6
Q
What do N-Methyl-D-Aspartate (NMDA) Receptor Antagonist treat?
A
- Alzheimer Disease
- Dementia
7
Q
Example of a N-Methyl-D-Aspartate (NMDA) Receptor Antagonist?
A
memantine
8
Q
What are rare adverse effects of memantine?
A
- dizziness, headache and confusion
- agitation, delusion, hallucinations
