histamine 2 receptor antagonists/ cimetidine (tagamet) Flashcards

1
Q

the drugs listed are called ____
Cimetidine [Tagamet]
Ranitidine [Zantac]
Famotidine [Pepcid]
Nizatidine [Axid

A

histamine 2 receptor antagonists

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2
Q

when taking cimetidine (tagamet); the theophylline dose needs to be _____while taking this medication

A

reduced

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3
Q

_______ are the first choice drugs for treating gastric and duodenal ulcers

A

histamine 2 receptor antagonists

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4
Q

histamine 2 receptors promote healing by suppressing secretion of _________

A

suppresses gastric acid

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5
Q

all four are equally ____

A

effective

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6
Q

serious side effects are _______

A

uncommon

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7
Q

H2Rantagonist cimetidine (tagamet) is absorbed slowly if taken with ________

A

meals

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8
Q

cimetidine (tagamet) cross the ____ ____ barrier with difficultly

A

blood brain barrier

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9
Q

cimetidine (tagamet) may cause _____ symptoms such as dizziness; drowsiness; headache

A

CNS symptoms

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10
Q

what are the therapeutic uses that H2R antagonist cimetidine (tagamet) used for

A

gastric and duodenal ulcers
GERD
Zollinger- Ellison syndrome
aspiration pneumonitis
heartburn; acid indigestion; sour stomach

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11
Q

adverse effects of cimetidine (tagamet)

A

antiandrogenic effects
CNS effects
pneumonia
IV bolus

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12
Q

adverse effects of cimetidine (tagamet) IV bolus can cause

A

hypotension and dysrhythmias

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13
Q

drug interactions of cimetidine (tagamet)

A

warfarin; theophylline; lidocaine; antacids

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14
Q

taking cimetidine (tagamet) with antacids can reduce absorption of ________

A

cimetidine (tagamet)

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15
Q

cimetidine and antacids should be administered at least _____ hour apart

A

1 hr apart

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