PPI drugs Flashcards
_____ is the first available PPI
omeprazole ( prilosec)
omeprazole (prilosec) inhibits gastric secretion by reducing ________ (heartburn)
dyspepsia (heartburn)
omeprazole (prilosec) has a ______ half life
short half life
omeprazole is used as a ______ term therapy
short term therapy
omeprazole (prilosec) ulcer prophylaxis is indicated only for patients in ________ and only if they have an additional risk factors such as _______
ICU and risk factors such as multiple trauma; spinal cord injury; prolonged mechanical ventilation ( longer than 48hrs)
adverse effects of omeprazole (prilosec) include
usually inconsequential for short term use fractures; headache; GI effects; pneumonia; hypomagnesemia; rebound hypersecretion; c. diff infection; and gastric cancer
________ aka [Nexium, Nexium IV] is nearly identical to omeprazole (prilosec)
esomeprazole
esomeprazole ( nexium; nexium IV) therapeutic uses are for
Erosive esophagitis, GERD, duodenal ulcers associated with H. pylori infection, prophylaxis of NSAID-induced ulcers
adverse effects of esomeprazole include )___
Headache, diarrhea, nausea, flatulence, abdominal pain, dry mouth, pneumonia, hypomagnesemia, osteoporosis, fractures
Lansoprazole [Prevacid, Prevacid IV, Prevacid 24 HR] is very similar to _______
omeprazole
adverse effects of Lansoprazole [Prevacid, Prevacid IV, Prevacid 24 HR] include
Diarrhea, abdominal pain, nausea, pneumonia, hypomagnesemia, osteoporosis, fracture
_______ is similar to omeprazole and other PPIs
Pantoprazole [Protonix]
Pantoprazole [Protonix] is used to treat
Treatment of GERD and hypersecretory states
Oral adverse effects of Pantoprazole [Protonix] are
diarrhea; headache; and dizziness
IV adverse effects of Pantoprazole [Protonix] are
headache, nausea, dyspepsia, injection-site reactions, including thrombophlebitis and abscess
