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Pathology II > Cysts and Odontogenic Tumors Part 2 > Flashcards

Cysts and Odontogenic Tumors Part 2 Flashcards

1
Q

where is the globulomaxillary position

A

at the junction of the maxilla with premaxilla, between maxillary lateral incisor and canine

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2
Q

is there a developmental fissural cyst in the globulomaxillary position

A

no

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3
Q

a developmental “globulomaxillary cyst”:

A

does not exist

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4
Q

what cysts are found in the globulomaxillary position and what is the prevalence of each

A
  • PA cyst: 50%
  • PA granuloma: 15%
  • lateral periodontal cyst: 10%
  • odontogenic keratocyst: 10%
  • giant cell tumor: 7%
  • other lesions: 3% such as gorlin cyst, odontogenic myxoma, adenomatoid odontogenic tumor, neurofibroma, hemangioma
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5
Q

what are the dental lamina cysts

A
  • lateral periodontal cysts
  • botryoid odontogenic cyst
  • gingiva cyst of adult
  • dental lamina cyst of newborn
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6
Q

describe the lateral periodontal cyst and its prevalance

A
  • a developmental cyst that arises from dental lamina rests (rests of Serres)
  • vital teeth of adult males (3:1)
  • mandibular premolar area
  • maxillary incisor-canine area
  • unilocular
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7
Q

what is the DDX for lateral periodontal cyst

A

PA cyst

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8
Q

what is the tx for lateral periodontal cyst

A

surgery

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9
Q

what is the histological presentation for lateral periodontal cyst

A
  • epithelium, lumen, wall
  • epithelium alternates thick and thin areas
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10
Q

describe the botyroid odontogenic cyst

A
  • polycystic variant of the lateral periodontal cyst
  • a developmental odontogenic cyst that presents as a multilocular lucency associated with the vital mandibular premolars of adults
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11
Q

describe the gingival cyst of the adult and the prevalance

A
  • soft tissue counterpart of the lateral periodontal cyst
  • no radiographic presenation
  • a developmental cyst that arises from dental lamina rests (rests of Serres)
  • vital teeth of adult males (3:1)
  • mandibular premolar area and. maxillary incisor-canine area
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12
Q

what is the histological presentation of gingival cyst of the adult

A

alternating thick and thin epithelium

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13
Q

what is the tx for the dental lamina cyst of the newborn

A

will usually resolve on their own

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14
Q

what is the histological presentation of the dental lamina cyst of the newborn

A

mutliple cystic areas filled with keratin

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15
Q

what are the other names for the palatal cyst of the newborn

A
  • epstein’s pearls
  • Bohn’s nodule
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16
Q

describe dental lamina cysts

A
  • epithelial remnants of dental lamina from odontogenesis
  • odontogenic cysts
17
Q

describe epstein’s pearls

A
  • epithelial remnants from palatal shelf fusion
  • non-odontogenic cysts
18
Q

describe Bohn’s nodules

A
  • epithelial remnants from minor salivary gland formation
  • non-odontogenic cysts
19
Q

describe primordial cysts

A
  • radiographic dx only
  • radiographic term for a cyst that develops in place of a tooth
  • likely to be an OKC
  • found in an area of a congenitally missing tooth
20
Q

what is the DDX for primordial cyst

A

residual cyst

21
Q

describe OKCs

A
  • posterior jaws of teenagers, young adults
  • aggressive growth with 30% recurrence
  • a unilocular or multilocular radiolucency; imitates other lucencies
22
Q

what are the radiographic presentations of OKCs and the prevelance of each

A
  • primordial cysts: 50%
  • lateral periodontal: 25%
  • dentigerous: 10%
  • globulomaxillary:10%
23
Q

what is the histology for an odontogenic keratocyst

A
  • compact epithelium, no rete ridges, 8 to 10 cell layers thick
  • corrugated surface parakeratin
  • prominent, palisaded, hyperchromatic basal layer
24
Q

what is the histologic presentation of an OKC

A
  • epithelium is thin
  • basal cell layer is really dark
  • keratin is wavy
25
Q

what is the significance of the odontogenic keratocyst

A
  • aggressive behavior
  • recurrence- 30%
  • nevoid basal cell carcinoma syndrome
26
Q

what is the cause of non-syndrome associated OKC

A

idiopathic

27
Q

what is the cause of syndrome associated OKC

A

multiple OKCs common in the nevoid basal cell carcinoma syndrome

28
Q

what is the other name for nevoid basal cell carcinoma syndrome

A

gorlin syndrome

29
Q

describe nevoid basal cell carcinoma syndrome

A
  • basal cell nevus syndrome
  • gorling-goltz syndrome
  • gorlin syndrome
  • autosomal dominant- highly penetrant and variably expressive
  • mutation in PTCH tumor suppressor gene at 9q22.3
30
Q

what are the features of the nevoid basal cell carcinoma syndrome

A
  • skeletal anomalies: bifid ribs
  • jaw cysts: multiple OKCs
  • skin tumors: multiple, early onset, basal cell carcinomas
  • neoplasms- CNS- medulloblastoma
31
Q

when do multiple basal cell carcinomas in nevoid basal cell carcinoma syndrome occur

A

early in life

32
Q

what should you do in early recognition and dx of nevoid basal cell carcinoma syndrome

A
  • OKCs present early
  • prevent disfiguring basal cell carcinomas
  • evaluate for medulloblastoma
33
Q

describe the orthokeratinizing odontogenic cyst

A
  • a developmental odontogenic cyst with an orthokeratin lining, NOT parakeratin
  • originally described as the “orthokeratinized variant of the odontogenic keratocyst”
  • does not behave as an odontogenic keratocyst- no recurrence
34
Q

what is the difference between histology of OKC and OOC

A
  • OKC is wavy and palisading
  • OOC is not wavy and not palisading
35
Q

describe the calcifying odontogenic cyst (Gorlin cyst)

A
  • gorlin cyst, calcifying and keratinizing odontogenic cyst
  • anterior jaws of adults
  • radiolucent to mixed
  • ghost cells
  • sometimes associated with odontomas
36
Q

describe the glandular odontogenic cyst

A

-sialodontogenic cyst- an odontogenic cyst with glandular (salivary) features
- anterior jaws of middle aged adults, mandible > maxilla
- commonly multilocular, crosses midline
- aggressive behavior - 30% recurrence

37
Q
A

Pathology II (19 decks)

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