MSK Flashcards

1
Q

what are the age related changes that we see in muscle with older adults

A

the cross sectional area of the muscles is reduced

fewer motor units to recruit - loss of motor neruons in the ventral horn of the spinal cord

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2
Q

how does a decrease in the cross sectional area of the muscle impact the muscle

A

less force is produced - less muscle to produce this force

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3
Q

what is the response of resistance training in older adults

A

increased recruitment much more then muscle hypertrophy

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4
Q

when does decreased muscle force production start

A

45

more rapid at 70

LE>UE

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5
Q

decreased cross sectional area is realted to the loss of what kind of fibers

A

fast twitch fiber area

slow twitch remain while fast decrease

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6
Q

what is muscle mass

A

how much muscle fiber is present

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7
Q

what is muscle strength

A

the ability to generate max muscle force

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8
Q

what is muscle power

A

the product of the force the the velocity of the contraction (time)

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9
Q

what characteristic of muscles is best at predicting disability

A

muscle power/ muscle strength

  • we can lose a lot of strength and still walk fine, walking does not use much strength
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10
Q

what does a loss of muscle power limit

A

stair negotiation

getting up from chairs

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11
Q

do our capillaries change size as we age

A

no in active elderly

sedentary elderly - have a decrease in capilliziation

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12
Q

what implication does decreased capillierization have

A

the decreased ability to shunt blood to active tissues - reduced effectiveness of vasodilation with activity

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13
Q

do we see changes with anerobic/aerobic dilation with aging

A

no

slight for aerobic - sedentary adult 20-30% change

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14
Q

what happens with aged cartilage

A

it cannot hold its water

  • aggrecan (protoglycan of art cart) cannot hold its water
  • hydrostatic lubrication is impaired, we will lose protection against compressive forces
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15
Q

what do chnages in the cart lead to

A

cracking and fribrillation

this disrupts the binding of fribonectin and lamin

the cart is exposed to degenerative enzymes - contributes to OA

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16
Q

why is the collegen in older adults rigid

A

the collagen is less souble, have cross linkages to stabilze it therefore it is more rigid

17
Q

what happen to the elastin in older adults

A

less is produced
more is fragmented

result:
- greater chance of rupture
- loss of rebound property

18
Q

what part of the body do we find elastin fibers

A

alveoli
aorta
lig flavum of the spine

19
Q

why do we see bone demineralization in older adults

A

reduced bone formation

age: reduced ability to make bone, bone formation is bad

postmenopausal women: bone reabsorption faster then bone formation

20
Q

what are the three factors to stimulate bone formation

A

WBearing

circulation

muscle contraction

21
Q

can exercise impact age related bone loss

A

yes but it takes a lot of exercise

22
Q

impact activties and bone formation

A

large loads

rapid changing directions

23
Q

endocrine impacts of exercise

A

exercise enhances insulin sensitivity, glucose metabolism, and some mito function