Gastroenterology

Question 1

What antibodies are positive in Primary Biliary Cholangitis?

Answer 1

Anti-mitochondrial antibodies

Question 2

Which antibodies are positive in auto-immune hepatitis?

Answer 2

Anti-smooth muscle antibodies
Anti-nuclear antibodies

Question 3

Which cancer is associated with coeliac and what is the investigation of choice for this?

Answer 3

Small bowel lymphoma
MRI abdomen

Question 4

What is the difference between hepatorenal syndrome type 1 and 2?

Answer 4

Type 1: triggered by acute event (SBP or haemorrhage), rapid decline in renal function, weeks to live
Type 2: diuretic resistent ascites, gradual decline in renal function, months to live

Question 5

Which autoimmune liver disease is associated with UC and how is it diagnosed and treated?

Answer 5

Primary Sclerosing Cholangitis
MRCP
Liver transplant

Question 6

Management of Autoimmune hepatitis

Answer 6

1. Prednisolone
2. a avathioprine
3. b mycophenolate
4. Ciclosporin or methotrexate

Question 7

Amyloidosis leading to heart failure Rx

Answer 7

Tafamidis

Question 8

Amyloidosis leading to neuropathy Rx

Answer 8

Inotersen

Question 9

Familial Mediterranean fever treatment

Answer 9

Colchicine