Lupus

Question 1

what is the most common type of Lupus?

Answer 1

systemic lupus erythematous

Question 2

chronic long-lasting autoimmune disease causing widespread inflammation and tissue damage involving multiple organs

Answer 2

systemic lupus erythematous

Question 3

which ethnicity is SLE most common in?

Answer 3

African Americans

Question 4

which patients is SLE most common in?

Answer 4

females in childbearing years

Question 5

which condition can occur with SLE?

Answer 5

rheumatoid arthritis

Question 6

what are 3 constitutional symptoms of SLE?

Answer 6

fever
fatigue
weight changes

Question 7

what 4 cutaneous symptoms can occur in SLE?

Answer 7

malar/butterfly rash (over cheeks and nose)
photosensitivity
oral/nasal ulcers
alopecia

Question 8

what 2 MSK symptoms occur in SLE?

Answer 8

arthralgias
arthritis (non-erosive)

Question 9

what is the most common pulmonary finding in SLE?

Answer 9

pleuritis

Question 10

involvement of what system in SLE indicates a worse prognosis?

Answer 10

CNS

Question 11

what is the ACR criteria to diagnose SLE?

Answer 11

4/11

Serositis
Oral ulcers
Arthritis
Photosensitivity

Blood disorders
Renal
ANA +
Immunologic
Neurologic

Malar rash
Discoid rash

Question 12

acute cutaneous lupus erythematosus that is also known as butterfly rush, sharply demarcated, flat/raised, and not itchy

Answer 12

malar rash

Question 13

chronic cutaneous lupus erythematous that is disc shaped; raised erythematous plaques with adherent keratotic scales on the scalp, face, neck, or oral cavity. Presents with a ring around the lesions

Answer 13

discoid rash/lupus

Question 14

skin rash as a result of unusual reaction to sunlight, UVA< UVB, or visible light; occurs more than 1 week after sun exposure, can exacerbate systemic symptoms

Answer 14

photosensitivity

Question 15

what is recommended to patients with SLE for photosensitivity?

Answer 15

sun screen

Question 16

painless oral or nasal occurrences in SLE

Answer 16

ulcers

Question 17

where in the body is discoid lupus painful?

Answer 17

oral cavity

Question 18

what lab is found in over half of patients with SLE?

Answer 18

lymphopenia

Question 19

lab finding that correlates with disease activity, anemia, and renal disease in SLE

Answer 19

ESR

Question 20

patients with SLE with serositis or infection will lead to an increase in which lab?

Answer 20

CRP

Question 21

which lab can rule out SLE if negative?

Answer 21

ANA

Question 22

which 2 labs can rule in SLE?

Answer 22

anti-smith
anti-dsDNA

Question 23

which lab will indicate drug-induced lupus?

Answer 23

anti-histone antibody

Question 24

which 2 labs will indicate neonatal lupus?

Answer 24

anti-Ro/SSA
anti-La/SSB

Question 25

how will complements be affected in SLE?

Answer 25

decreased

Question 26

what will be found in urinalysis in SLE? (2)

Answer 26

proteinuria
hematuria

Question 27

what is the management/treatment for SLE? (3)

Answer 27

NSAIDS (arthralgia)
steroids (exacerbations)
hydroxychloroquine (long-term)

Question 28

what is the treatment for active glomerulonephritis?

Answer 28

cytotoxic agents

Question 29

what exam should be done every year when diagnosed with SLE?

Answer 29

visual exam for risk of retinal toxicity