RBC EXTRINSIC DEFECTS: NON-IMMUNE CAUSES Flashcards
1
Q
Formation of schistocyte/ RBC
fragment
A
Microangiopathic Hemolytic anemia (MAHA)
2
Q
due to deficiency of ADAMTS13 due to cutting of VWF
A
Thrombotic thrombocytopenic purpura (TTP)
3
Q
due to E. coli OL57:H7- produces shiga like toxin
A
Hemolytic uremic syndrome (HUS)
4
Q
Hemolysis, elevated liver enzymes, low platele. count syndrome- low plt ct and clotting factors
A
HELLP
5
Q
Thrombotic thrombocytopenic purpura- due to
deficiency of _____ due to cutting of VWF
A
ADAMTS13
6
Q
HUS - Hemolytic uremic syndrome- due to ______ produces shiga like toxin
A
E. coli OL57:H7
7
Q
Hemolytic Anemia caused by Infectious agents
examples
A
Malaria
Babesiosis
8
Q
Hemolytic Anemia caused by RBC injuries
examples
A
drugs/chemicals
venoms
extensive burns